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Heparin inhibits intracellular Mycobacterium tuberculosis bacterial replication by reducing iron levels in human macrophages
Iron is a crucial micronutrient for both mammals and their associated pathogens, and extensive literature has shown that Mycobacterium tuberculosis (Mtb) bacilli inhibited from acquiring iron from the host are severely attenuated. In contrast, increased dietary iron concentrations or patients with h...
Autores principales: | Abreu, Rodrigo, Essler, Lauren, Loy, Allyson, Quinn, Frederick, Giri, Pramod |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940867/ https://www.ncbi.nlm.nih.gov/pubmed/29740038 http://dx.doi.org/10.1038/s41598-018-25480-y |
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