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NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells

NOTCH signaling is required for the arterial specification and formation of hematopoietic stem cells (HSCs) and lympho-myeloid progenitors in the embryonic aorta-gonad-mesonephros region and extraembryonic vasculature from a distinct lineage of vascular endothelial cells with hemogenic potential. Ho...

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Detalles Bibliográficos
Autores principales:	Uenishi, Gene I., Jung, Ho Sun, Kumar, Akhilesh, Park, Mi Ae, Hadland, Brandon K., McLeod, Ethan, Raymond, Matthew, Moskvin, Oleg, Zimmerman, Catherine E., Theisen, Derek J., Swanson, Scott, J. Tamplin, Owen, Zon, Leonard I., Thomson, James A., Bernstein, Irwin D., Slukvin, Igor I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940870/ https://www.ncbi.nlm.nih.gov/pubmed/29739946 http://dx.doi.org/10.1038/s41467-018-04134-7

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