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NADH/NADPH bi-cofactor-utilizing and thermoactive ketol-acid reductoisomerase from Sulfolobus acidocaldarius

Ketol-acid reductoisomerase (KARI) is a bifunctional enzyme in the second step of branched-chain amino acids biosynthetic pathway. Most KARIs prefer NADPH as a cofactor. However, KARI with a preference for NADH is desirable in industrial applications including anaerobic fermentation for the producti...

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Detalles Bibliográficos
Autores principales:	Chen, Chin-Yu, Ko, Tzu-Ping, Lin, Kuan-Fu, Lin, Bo-Lin, Huang, Chun-Hsiang, Chiang, Cheng-Hung, Horng, Jia-Cherng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940873/ https://www.ncbi.nlm.nih.gov/pubmed/29739976 http://dx.doi.org/10.1038/s41598-018-25361-4

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