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Properties of Zinc Oxide Nanoparticles and Their Activity Against Microbes
Zinc oxide is an essential ingredient of many enzymes, sun screens, and ointments for pain and itch relief. Its microcrystals are very efficient light absorbers in the UVA and UVB region of spectra due to wide bandgap. Impact of zinc oxide on biological functions depends on its morphology, particle...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940970/ https://www.ncbi.nlm.nih.gov/pubmed/29740719 http://dx.doi.org/10.1186/s11671-018-2532-3 |
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author | Siddiqi, Khwaja Salahuddin ur Rahman, Aziz Tajuddin Husen, Azamal |
author_facet | Siddiqi, Khwaja Salahuddin ur Rahman, Aziz Tajuddin Husen, Azamal |
author_sort | Siddiqi, Khwaja Salahuddin |
collection | PubMed |
description | Zinc oxide is an essential ingredient of many enzymes, sun screens, and ointments for pain and itch relief. Its microcrystals are very efficient light absorbers in the UVA and UVB region of spectra due to wide bandgap. Impact of zinc oxide on biological functions depends on its morphology, particle size, exposure time, concentration, pH, and biocompatibility. They are more effective against microorganisms such as Bacillus subtilis, Bacillus megaterium, Staphylococcus aureus, Sarcina lutea, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Pseudomonas vulgaris, Candida albicans, and Aspergillus niger. Mechanism of action has been ascribed to the activation of zinc oxide nanoparticles by light, which penetrate the bacterial cell wall via diffusion. It has been confirmed from SEM and TEM images of the bacterial cells that zinc oxide nanoparticles disintegrate the cell membrane and accumulate in the cytoplasm where they interact with biomolecules causing cell apoptosis leading to cell death. |
format | Online Article Text |
id | pubmed-5940970 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-59409702018-05-14 Properties of Zinc Oxide Nanoparticles and Their Activity Against Microbes Siddiqi, Khwaja Salahuddin ur Rahman, Aziz Tajuddin Husen, Azamal Nanoscale Res Lett Nano Review Zinc oxide is an essential ingredient of many enzymes, sun screens, and ointments for pain and itch relief. Its microcrystals are very efficient light absorbers in the UVA and UVB region of spectra due to wide bandgap. Impact of zinc oxide on biological functions depends on its morphology, particle size, exposure time, concentration, pH, and biocompatibility. They are more effective against microorganisms such as Bacillus subtilis, Bacillus megaterium, Staphylococcus aureus, Sarcina lutea, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Pseudomonas vulgaris, Candida albicans, and Aspergillus niger. Mechanism of action has been ascribed to the activation of zinc oxide nanoparticles by light, which penetrate the bacterial cell wall via diffusion. It has been confirmed from SEM and TEM images of the bacterial cells that zinc oxide nanoparticles disintegrate the cell membrane and accumulate in the cytoplasm where they interact with biomolecules causing cell apoptosis leading to cell death. Springer US 2018-05-08 /pmc/articles/PMC5940970/ /pubmed/29740719 http://dx.doi.org/10.1186/s11671-018-2532-3 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Nano Review Siddiqi, Khwaja Salahuddin ur Rahman, Aziz Tajuddin Husen, Azamal Properties of Zinc Oxide Nanoparticles and Their Activity Against Microbes |
title | Properties of Zinc Oxide Nanoparticles and Their Activity Against Microbes |
title_full | Properties of Zinc Oxide Nanoparticles and Their Activity Against Microbes |
title_fullStr | Properties of Zinc Oxide Nanoparticles and Their Activity Against Microbes |
title_full_unstemmed | Properties of Zinc Oxide Nanoparticles and Their Activity Against Microbes |
title_short | Properties of Zinc Oxide Nanoparticles and Their Activity Against Microbes |
title_sort | properties of zinc oxide nanoparticles and their activity against microbes |
topic | Nano Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940970/ https://www.ncbi.nlm.nih.gov/pubmed/29740719 http://dx.doi.org/10.1186/s11671-018-2532-3 |
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