Progress in the biological function of alpha-enolase

Alpha-enolase (ENO1), also known as 2-phospho-D-glycerate hydrolase, is a metalloenzyme that catalyzes the conversion of 2-phosphoglyceric acid to phosphoenolpyruvic acid in the glycolytic pathway. It is a multifunctional glycolytic enzyme involved in cellular stress, bacterial and fungal infections...

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Detalles Bibliográficos
Autores principales: Ji, Hong, Wang, Jianfa, Guo, Jingru, Li, Yue, Lian, Shuai, Guo, Wenjin, Yang, Huanmin, Kong, Fanzhi, Zhen, Li, Guo, Li, Liu, Yanzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941012/
https://www.ncbi.nlm.nih.gov/pubmed/29767008
http://dx.doi.org/10.1016/j.aninu.2016.02.005
Descripción
Sumario:Alpha-enolase (ENO1), also known as 2-phospho-D-glycerate hydrolase, is a metalloenzyme that catalyzes the conversion of 2-phosphoglyceric acid to phosphoenolpyruvic acid in the glycolytic pathway. It is a multifunctional glycolytic enzyme involved in cellular stress, bacterial and fungal infections, autoantigen activities, the occurrence and metastasis of cancer, parasitic infections, and the growth, development and reproduction of organisms. This article mainly reviews the basic characteristics and biological functions of ENO1.

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