Cargando…

Progress in the biological function of alpha-enolase

Alpha-enolase (ENO1), also known as 2-phospho-D-glycerate hydrolase, is a metalloenzyme that catalyzes the conversion of 2-phosphoglyceric acid to phosphoenolpyruvic acid in the glycolytic pathway. It is a multifunctional glycolytic enzyme involved in cellular stress, bacterial and fungal infections...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, Hong, Wang, Jianfa, Guo, Jingru, Li, Yue, Lian, Shuai, Guo, Wenjin, Yang, Huanmin, Kong, Fanzhi, Zhen, Li, Guo, Li, Liu, Yanzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941012/
https://www.ncbi.nlm.nih.gov/pubmed/29767008
http://dx.doi.org/10.1016/j.aninu.2016.02.005
_version_ 1783321206677569536
author Ji, Hong
Wang, Jianfa
Guo, Jingru
Li, Yue
Lian, Shuai
Guo, Wenjin
Yang, Huanmin
Kong, Fanzhi
Zhen, Li
Guo, Li
Liu, Yanzhi
author_facet Ji, Hong
Wang, Jianfa
Guo, Jingru
Li, Yue
Lian, Shuai
Guo, Wenjin
Yang, Huanmin
Kong, Fanzhi
Zhen, Li
Guo, Li
Liu, Yanzhi
author_sort Ji, Hong
collection PubMed
description Alpha-enolase (ENO1), also known as 2-phospho-D-glycerate hydrolase, is a metalloenzyme that catalyzes the conversion of 2-phosphoglyceric acid to phosphoenolpyruvic acid in the glycolytic pathway. It is a multifunctional glycolytic enzyme involved in cellular stress, bacterial and fungal infections, autoantigen activities, the occurrence and metastasis of cancer, parasitic infections, and the growth, development and reproduction of organisms. This article mainly reviews the basic characteristics and biological functions of ENO1.
format Online
Article
Text
id pubmed-5941012
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher KeAi Publishing
record_format MEDLINE/PubMed
spelling pubmed-59410122018-05-14 Progress in the biological function of alpha-enolase Ji, Hong Wang, Jianfa Guo, Jingru Li, Yue Lian, Shuai Guo, Wenjin Yang, Huanmin Kong, Fanzhi Zhen, Li Guo, Li Liu, Yanzhi Anim Nutr Review Alpha-enolase (ENO1), also known as 2-phospho-D-glycerate hydrolase, is a metalloenzyme that catalyzes the conversion of 2-phosphoglyceric acid to phosphoenolpyruvic acid in the glycolytic pathway. It is a multifunctional glycolytic enzyme involved in cellular stress, bacterial and fungal infections, autoantigen activities, the occurrence and metastasis of cancer, parasitic infections, and the growth, development and reproduction of organisms. This article mainly reviews the basic characteristics and biological functions of ENO1. KeAi Publishing 2016-03 2016-03-02 /pmc/articles/PMC5941012/ /pubmed/29767008 http://dx.doi.org/10.1016/j.aninu.2016.02.005 Text en © 2016, Chinese Association of Animal Science and Veterinary Medicine. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Ji, Hong
Wang, Jianfa
Guo, Jingru
Li, Yue
Lian, Shuai
Guo, Wenjin
Yang, Huanmin
Kong, Fanzhi
Zhen, Li
Guo, Li
Liu, Yanzhi
Progress in the biological function of alpha-enolase
title Progress in the biological function of alpha-enolase
title_full Progress in the biological function of alpha-enolase
title_fullStr Progress in the biological function of alpha-enolase
title_full_unstemmed Progress in the biological function of alpha-enolase
title_short Progress in the biological function of alpha-enolase
title_sort progress in the biological function of alpha-enolase
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941012/
https://www.ncbi.nlm.nih.gov/pubmed/29767008
http://dx.doi.org/10.1016/j.aninu.2016.02.005
work_keys_str_mv AT jihong progressinthebiologicalfunctionofalphaenolase
AT wangjianfa progressinthebiologicalfunctionofalphaenolase
AT guojingru progressinthebiologicalfunctionofalphaenolase
AT liyue progressinthebiologicalfunctionofalphaenolase
AT lianshuai progressinthebiologicalfunctionofalphaenolase
AT guowenjin progressinthebiologicalfunctionofalphaenolase
AT yanghuanmin progressinthebiologicalfunctionofalphaenolase
AT kongfanzhi progressinthebiologicalfunctionofalphaenolase
AT zhenli progressinthebiologicalfunctionofalphaenolase
AT guoli progressinthebiologicalfunctionofalphaenolase
AT liuyanzhi progressinthebiologicalfunctionofalphaenolase