Cargando…

Bone Marrow Is a Major Parasite Reservoir in Plasmodium vivax Infection

Plasmodium vivax causes heavy burdens of disease across malarious regions worldwide. Mature P. vivax asexual and transmissive gametocyte stages occur in the blood circulation, and it is often assumed that accumulation/sequestration in tissues is not an important phase in their development. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Obaldia, Nicanor, Meibalan, Elamaran, Sa, Juliana M., Ma, Siyuan, Clark, Martha A., Mejia, Pedro, Moraes Barros, Roberto R., Otero, William, Ferreira, Marcelo U., Mitchell, James R., Milner, Danny A., Huttenhower, Curtis, Wirth, Dyann F., Duraisingh, Manoj T., Wellems, Thomas E., Marti, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941073/ https://www.ncbi.nlm.nih.gov/pubmed/29739900 http://dx.doi.org/10.1128/mBio.00625-18

Ejemplares similares

Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model
por: Obaldía III, Nicanor, et al.
Publicado: (2016)

Insights into an Optimization of Plasmodium vivax Sal-1 In Vitro Culture: The Aotus Primate Model
por: Shaw-Saliba, Kathryn, et al.
Publicado: (2016)

Determinants of low socio-economic status and risk of Plasmodium vivax malaria infection in Panama (2009–2012): a case–control study
por: Obaldia, Nicanor
Publicado: (2015)

Plasmodium gametocytes display homing and vascular transmigration in the host bone marrow
por: De Niz, Mariana, et al.
Publicado: (2018)

On the survival of 48 h Plasmodium vivax Aotus monkey-derived ex vivo cultures: the role of leucocytes filtration and chemically defined lipid concentrate media supplementation
por: Obaldía, Nicanor, et al.
Publicado: (2020)

The molecular basis of antimalarial drug resistance in Plasmodium vivax
por: Buyon, Lucas E., et al.
Publicado: (2021)

Evidence for spleen dysfunction in malaria-HIV co-infection in a subset of pediatric patients
por: Joice, Regina, et al.
Publicado: (2016)

Comparison of PvLAP5 and Pvs25 qRT-PCR assays for the detection of Plasmodium vivax gametocytes in field samples preserved at ambient temperature from remote malaria endemic regions of Panama
por: Obaldía, Nicanor, et al.
Publicado: (2022)

Persistence of Plasmodium falciparum parasitemia after artemisinin combination therapy: evidence from a randomized trial in Uganda
por: Chang, Hsiao-Han, et al.
Publicado: (2016)

Population genomics of Plasmodium vivax in Panama to assess the risk of case importation on malaria elimination
por: Buyon, Lucas E., et al.
Publicado: (2020)

Development of a Single Nucleotide Polymorphism Barcode to Genotype Plasmodium vivax Infections
por: Baniecki, Mary Lynn, et al.
Publicado: (2015)

Plasmodium vivax infection compromises reticulocyte stability
por: Clark, Martha A., et al.
Publicado: (2021)

Modelling the contribution of the hypnozoite reservoir to Plasmodium vivax transmission
por: White, Michael T, et al.
Publicado: (2014)

Superinfection and the hypnozoite reservoir for Plasmodium vivax: a general framework
por: Mehra, Somya, et al.
Publicado: (2023)

Long read single cell RNA sequencing reveals the isoform diversity of Plasmodium vivax transcripts
por: Hazzard, Brittany, et al.
Publicado: (2022)

Single-cell transcription analysis of Plasmodium vivax blood-stage parasites identifies stage- and species-specific profiles of expression
por: Sà, Juliana M., et al.
Publicado: (2020)

Dietary restriction protects against experimental cerebral malaria via leptin modulation and T cell mTORC1 suppression
por: Mejia, Pedro, et al.
Publicado: (2015)

Inferring Developmental Stage Composition from Gene Expression in Human Malaria
por: Joice, Regina, et al.
Publicado: (2013)

Plasmodium vivax transcriptional profiling of low input cryopreserved isolates through the intraerythrocytic development cycle
por: Rangel, Gabriel W., et al.
Publicado: (2020)

A Large Plasmodium vivax Reservoir and Little Population Structure in the South Pacific
por: Koepfli, Cristian, et al.
Publicado: (2013)

Activity of Plasmodium vivax promoter elements in Plasmodium knowlesi, and a centromere-containing plasmid that expresses NanoLuc throughout the parasite life cycle
por: Moraes Barros, Roberto R., et al.
Publicado: (2021)

Development of a Plasmodium vivax biobank for functional ex vivo assays
por: Dash, Rashmi, et al.
Publicado: (2023)

Plasmodium falciparum Gametocyte Density and Infectivity in Peripheral Blood and Skin Tissue of Naturally Infected Parasite Carriers in Burkina Faso
por: Meibalan, Elamaran, et al.
Publicado: (2019)

Identification of the asymptomatic Plasmodium falciparum and Plasmodium vivax gametocyte reservoir under different transmission intensities
por: Koepfli, Cristian, et al.
Publicado: (2021)

A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs
por: Broadbent, Kate M, et al.
Publicado: (2011)

Evaluation of splenic accumulation and colocalization of immature reticulocytes and Plasmodium vivax in asymptomatic malaria: A prospective human splenectomy study
por: Kho, Steven, et al.
Publicado: (2021)

Adipose tissue parasite sequestration drives leptin production in mice and correlates with human cerebral malaria
por: Mejia, Pedro, et al.
Publicado: (2021)

Use of a Plasmodium vivax genetic barcode for genomic surveillance and parasite tracking in Sri Lanka
por: Dewasurendra, Rajika L., et al.
Publicado: (2020)

Plasmodium falciparum gene expression measured directly from tissue during human infection
por: Van Tyne, Daria, et al.
Publicado: (2014)

The structure of a Plasmodium vivax Tryptophan Rich Antigen domain suggests a lipid binding function for a pan-Plasmodium multi-gene family
por: Kundu, Prasun, et al.
Publicado: (2023)

Alternative methods for the Plasmodium falciparum artemisinin ring-stage survival assay with increased simplicity and parasite stage-specificity
por: Kite, Whitney A., et al.
Publicado: (2016)

Independent Origin and Global Distribution of Distinct Plasmodium vivax Duffy Binding Protein Gene Duplications
por: Hostetler, Jessica B., et al.
Publicado: (2016)

Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum
por: Patel, Vishal, et al.
Publicado: (2009)

Single-nucleotide polymorphism, linkage disequilibrium and geographic structure in the malaria parasite Plasmodium vivax: prospects for genome-wide association studies
por: Orjuela-Sánchez, Pamela, et al.
Publicado: (2010)

Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross
por: Sá, Juliana M., et al.
Publicado: (2019)

Potential hidden Plasmodium vivax malaria reservoirs from low parasitemia Duffy-negative Ethiopians: Molecular evidence
por: Abebe, Abnet, et al.
Publicado: (2023)

Genetic diversity of Plasmodium vivax and Plasmodium falciparum in Honduras
por: Lopez, Ana Cecilia, et al.
Publicado: (2012)

Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa
por: Happi, Christian T, et al.
Publicado: (2006)

A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking
por: Daniels, Rachel, et al.
Publicado: (2008)

Transcriptional Profiling of Plasmodium falciparum Parasites from Patients with Severe Malaria Identifies Distinct Low vs. High Parasitemic Clusters
por: Milner, Danny A., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_3kss2g6gj2sp6m5ghvp8m91519