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A case of periorbital necrotizing fasciitis rapidly progressing to severe multiorgan failure

Periorbital necrotizing fasciitis (PNF) is a severe suppurative infection of the subcutaneous tissue and underlying fascia of the periorbital region. Typically, the course of PNF is milder and has a better prognosis than that of necrotizing fasciitis in other parts of the body. As such, this disease...

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Detalles Bibliográficos
Autores principales: Eiben, Paola, Rodriguez-Villar, Sancho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941132/
https://www.ncbi.nlm.nih.gov/pubmed/29765591
http://dx.doi.org/10.1093/jscr/rjy083
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author Eiben, Paola
Rodriguez-Villar, Sancho
author_facet Eiben, Paola
Rodriguez-Villar, Sancho
author_sort Eiben, Paola
collection PubMed
description Periorbital necrotizing fasciitis (PNF) is a severe suppurative infection of the subcutaneous tissue and underlying fascia of the periorbital region. Typically, the course of PNF is milder and has a better prognosis than that of necrotizing fasciitis in other parts of the body. As such, this disease is thought to be associated with a significantly smaller risk of morbidity and mortality. Nevertheless, it is a rare and devastating condition that can lead to disfigurement, blindness and death. Early recognition is critical to improved patient outcomes. Here, we describe a case of PNF in a 60-year-old male that rapidly progressed to widespread systemic involvement and severe multiorgan failure requiring ventilatory, cardiovascular and renal support. Treatment included broad-spectrum antibiotics, intravenous immunoglobulin and surgical debridement. This case highlights the life-threatening nature of PNF, as demonstrated by rapid progression to multiorgan dysfunction and the need of an urgent surgical intervention.
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spelling pubmed-59411322018-05-15 A case of periorbital necrotizing fasciitis rapidly progressing to severe multiorgan failure Eiben, Paola Rodriguez-Villar, Sancho J Surg Case Rep Case Report Periorbital necrotizing fasciitis (PNF) is a severe suppurative infection of the subcutaneous tissue and underlying fascia of the periorbital region. Typically, the course of PNF is milder and has a better prognosis than that of necrotizing fasciitis in other parts of the body. As such, this disease is thought to be associated with a significantly smaller risk of morbidity and mortality. Nevertheless, it is a rare and devastating condition that can lead to disfigurement, blindness and death. Early recognition is critical to improved patient outcomes. Here, we describe a case of PNF in a 60-year-old male that rapidly progressed to widespread systemic involvement and severe multiorgan failure requiring ventilatory, cardiovascular and renal support. Treatment included broad-spectrum antibiotics, intravenous immunoglobulin and surgical debridement. This case highlights the life-threatening nature of PNF, as demonstrated by rapid progression to multiorgan dysfunction and the need of an urgent surgical intervention. Oxford University Press 2018-04-30 /pmc/articles/PMC5941132/ /pubmed/29765591 http://dx.doi.org/10.1093/jscr/rjy083 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Eiben, Paola
Rodriguez-Villar, Sancho
A case of periorbital necrotizing fasciitis rapidly progressing to severe multiorgan failure
title A case of periorbital necrotizing fasciitis rapidly progressing to severe multiorgan failure
title_full A case of periorbital necrotizing fasciitis rapidly progressing to severe multiorgan failure
title_fullStr A case of periorbital necrotizing fasciitis rapidly progressing to severe multiorgan failure
title_full_unstemmed A case of periorbital necrotizing fasciitis rapidly progressing to severe multiorgan failure
title_short A case of periorbital necrotizing fasciitis rapidly progressing to severe multiorgan failure
title_sort case of periorbital necrotizing fasciitis rapidly progressing to severe multiorgan failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941132/
https://www.ncbi.nlm.nih.gov/pubmed/29765591
http://dx.doi.org/10.1093/jscr/rjy083
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