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A case of rhabdomyolysis after kidney transplantation successfully managed with intensive continuous dialysis

Rhabdomyolysis is characterized by muscle cell death which can result in acute kidney injury from pigment nephropathy. We present a patient who developed rhabdomyolysis immediately after deceased donor kidney transplantation surgery and was managed with continuous renal replacement therapy that resu...

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Autores principales: Shahbazov, Rauf, Fox, Michael, Alejo, Jennifer L, Anjum, Malik A, Azari, Feredun, Doyle, Alden, Agarwal, Avinash, Brayman, Kenneth L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941162/
https://www.ncbi.nlm.nih.gov/pubmed/29765590
http://dx.doi.org/10.1093/jscr/rjy078
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author Shahbazov, Rauf
Fox, Michael
Alejo, Jennifer L
Anjum, Malik A
Azari, Feredun
Doyle, Alden
Agarwal, Avinash
Brayman, Kenneth L
author_facet Shahbazov, Rauf
Fox, Michael
Alejo, Jennifer L
Anjum, Malik A
Azari, Feredun
Doyle, Alden
Agarwal, Avinash
Brayman, Kenneth L
author_sort Shahbazov, Rauf
collection PubMed
description Rhabdomyolysis is characterized by muscle cell death which can result in acute kidney injury from pigment nephropathy. We present a patient who developed rhabdomyolysis immediately after deceased donor kidney transplantation surgery and was managed with continuous renal replacement therapy that resulted in successful salvage of the kidney allograft. Patients who develop acute kidney failure requiring renal replacement therapy generally have a poor prognosis. It is worth noting that while continuous veno-venous hemofiltration (CVVHF) offers greater volume support and continuous clearance compared to hemodialysis (HD), recent studies have demonstrated no clinically significant improvement in clinical outcome between the two. Perhaps CVVHF is a better modality compared to HD in this setting to prevent further insult from pigment nephropathy to an allograft. A combination of early diagnosis and intensive continuous renal replacement therapy can be used for allograft salvage in a patient with rhabdomyolysis in the immediate post-kidney transplant period.
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spelling pubmed-59411622018-05-15 A case of rhabdomyolysis after kidney transplantation successfully managed with intensive continuous dialysis Shahbazov, Rauf Fox, Michael Alejo, Jennifer L Anjum, Malik A Azari, Feredun Doyle, Alden Agarwal, Avinash Brayman, Kenneth L J Surg Case Rep Case Report Rhabdomyolysis is characterized by muscle cell death which can result in acute kidney injury from pigment nephropathy. We present a patient who developed rhabdomyolysis immediately after deceased donor kidney transplantation surgery and was managed with continuous renal replacement therapy that resulted in successful salvage of the kidney allograft. Patients who develop acute kidney failure requiring renal replacement therapy generally have a poor prognosis. It is worth noting that while continuous veno-venous hemofiltration (CVVHF) offers greater volume support and continuous clearance compared to hemodialysis (HD), recent studies have demonstrated no clinically significant improvement in clinical outcome between the two. Perhaps CVVHF is a better modality compared to HD in this setting to prevent further insult from pigment nephropathy to an allograft. A combination of early diagnosis and intensive continuous renal replacement therapy can be used for allograft salvage in a patient with rhabdomyolysis in the immediate post-kidney transplant period. Oxford University Press 2018-04-30 /pmc/articles/PMC5941162/ /pubmed/29765590 http://dx.doi.org/10.1093/jscr/rjy078 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Shahbazov, Rauf
Fox, Michael
Alejo, Jennifer L
Anjum, Malik A
Azari, Feredun
Doyle, Alden
Agarwal, Avinash
Brayman, Kenneth L
A case of rhabdomyolysis after kidney transplantation successfully managed with intensive continuous dialysis
title A case of rhabdomyolysis after kidney transplantation successfully managed with intensive continuous dialysis
title_full A case of rhabdomyolysis after kidney transplantation successfully managed with intensive continuous dialysis
title_fullStr A case of rhabdomyolysis after kidney transplantation successfully managed with intensive continuous dialysis
title_full_unstemmed A case of rhabdomyolysis after kidney transplantation successfully managed with intensive continuous dialysis
title_short A case of rhabdomyolysis after kidney transplantation successfully managed with intensive continuous dialysis
title_sort case of rhabdomyolysis after kidney transplantation successfully managed with intensive continuous dialysis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941162/
https://www.ncbi.nlm.nih.gov/pubmed/29765590
http://dx.doi.org/10.1093/jscr/rjy078
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