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Shared dynamics of LeuT superfamily members and allosteric differentiation by structural irregularities and multimerization
The LeuT-fold superfamily includes secondary active transporters from different functional families, which share a common tertiary structure, despite having a remarkably low sequence similarity. By identifying the common structural and dynamical features upon principal component analysis of a compre...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941172/ https://www.ncbi.nlm.nih.gov/pubmed/29735731 http://dx.doi.org/10.1098/rstb.2017.0177 |