Cargando…

Suppression of the interleukin-1β-induced inflammatory response of human Chang liver cells by acute and subacute exposure to alcohol: an in vitro study

AIM: To evaluate protective immunosuppressive dose and time-dependent effects of ethanol in an in vitro model of acute inflammation in human Chang liver cells. METHOD: The study was performed in 2016 and 2017 in the research laboratory of the Department of Trauma, Hand and Reconstructive Surgery, th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mörs, Katharina, Kany, Shinwan, Hörauf, Jason-Alexander, Wagner, Nils, Neunaber, Claudia, Perl, Mario, Marzi, Ingo, Relja, Borna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Croatian Medical Schools 2018
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941294/ https://www.ncbi.nlm.nih.gov/pubmed/29740988 http://dx.doi.org/10.3325/cmj.2018.59.46

Ejemplares similares

Anti-inflammatory Effects of Alcohol Are Associated with JNK-STAT3 Downregulation in an In Vitro Inflammation Model in HepG2 Cells
por: Mörs, Katharina, et al.
Publicado: (2021)

Innate Immunity and Alcohol
por: Kany, Shinwan, et al.
Publicado: (2019)

Reduced NLRP3 Gene Expression Limits the IL-1β Cleavage via Inflammasome in Monocytes from Severely Injured Trauma Patients
por: Kany, Shinwan, et al.
Publicado: (2018)

Short Exposure to Ethanol Diminishes Caspase-1 and ASC Activation in Human HepG2 Cells In Vitro
por: Hörauf, Jason-Alexander, et al.
Publicado: (2020)

Danger signals in trauma
por: Relja, Borna, et al.
Publicado: (2018)

Ethyl pyruvate ameliorates hepatic injury following blunt chest trauma and hemorrhagic shock by reducing local inflammation, NF-kappaB activation and HMGB1 release
por: Wagner, Nils, et al.
Publicado: (2018)

Cytokines in Inflammatory Disease
por: Kany, Shinwan, et al.
Publicado: (2019)

Reduced phagocytosis, ROS production and enhanced apoptosis of leukocytes upon alcohol drinking in healthy volunteers
por: Haag, Florian, et al.
Publicado: (2021)

Acute alcohol consumption increases systemic endotoxin bioactivity for days in healthy volunteers—with reduced intestinal barrier loss in female
por: Sturm, Ramona, et al.
Publicado: (2021)

Acute Alcohol Intoxication Modulates Monocyte Subsets and Their Functions in a Time-Dependent Manner in Healthy Volunteers
por: Janicova, Andrea, et al.
Publicado: (2021)

Circulating Extracellular Vesicles and Their miR “Barcode” Differentiate Alcohol Drinkers With Liver Injury and Those Without Liver Injury in Severe Trauma Patients
por: Eguchi, Akiko, et al.
Publicado: (2019)

Club Cell Protein 16 Attenuates CD16(bright)CD62(dim) Immunosuppressive Neutrophils in Damaged Tissue upon Posttraumatic Sepsis-Induced Lung Injury
por: Becker, Nils, et al.
Publicado: (2021)

Injury Patterns after Falling down Stairs—High Ratio of Traumatic Brain Injury under Alcohol Influence
por: Hörauf, Jason-Alexander, et al.
Publicado: (2022)

Modulation of Inflammation by Alcohol Exposure
por: Lehnert, Mark, et al.
Publicado: (2014)

Is I-FABP not only a marker for the detection abdominal injury but also of hemorrhagic shock in severely injured trauma patients?
por: Voth, Maika, et al.
Publicado: (2019)

Differential Relevance of NF-κB and JNK in the Pathophysiology of Hemorrhage/Resususcitation-Induced Liver Injury after Chronic Ethanol Feeding
por: Relja, Borna, et al.
Publicado: (2015)

Traumatic injury pattern is of equal relevance as injury severity for experimental (poly)trauma modeling
por: Yang, Bing, et al.
Publicado: (2019)

Early local neutralization of CC16 in sepsis-induced ALI following blunt chest trauma leads to delayed mortality without benefitting overall survival
por: Vollrath, Jan Tilmann, et al.
Publicado: (2020)

Sera from severe trauma patients with pneumonia and without infectious complications have differential effects on neutrophil biology
por: Relja, B., et al.
Publicado: (2016)

Severe Traumatic Injury Induces Phenotypic and Functional Changes of Neutrophils and Monocytes
por: Janicova, Andrea, et al.
Publicado: (2021)

Post-Traumatic Sepsis Is Associated with Increased C5a and Decreased TAFI Levels
por: Vollrath, Jan Tilmann, et al.
Publicado: (2020)

Different experimental multiple trauma models induce comparable inflammation and organ injury
por: Relja, Borna, et al.
Publicado: (2020)

Ethyl Pyruvate Reduces Systemic Leukocyte Activation via Caspase-1 and NF-κB After Blunt Chest Trauma and Haemorrhagic Shock
por: Dieteren, Scott, et al.
Publicado: (2020)

Adding to the evidence or to the confusion: dual antithrombotic therapy in chronic coronary syndrome and atrial fibrillation
por: Kany, Shinwan, et al.
Publicado: (2021)

The Impact of Acute or Chronic Alcohol Intake on the NF-κB Signaling Pathway in Alcohol-Related Liver Disease
por: Nowak, Aleksander J., et al.
Publicado: (2020)

Impact of age on liver damage, inflammation, and molecular signaling pathways in response to femoral fracture and hemorrhage
por: Meng, Fanshuai, et al.
Publicado: (2023)

Acute Intoxication With Alcohol Reduces Trauma-Induced Proinflammatory Response and Barrier Breakdown in the Lung via the Wnt/β-Catenin Signaling Pathway
por: Noack, Laurens, et al.
Publicado: (2022)

Circulating Leukotriene B4 Identifies Respiratory Complications after Trauma
por: Auner, Birgit, et al.
Publicado: (2012)

Early Local Inhibition of Club Cell Protein 16 Following Chest Trauma Reduces Late Sepsis-Induced Acute Lung Injury
por: Störmann, Philipp, et al.
Publicado: (2019)

Selective Inhibition of IL-6 Trans-Signaling Has No Beneficial Effect on the Posttraumatic Cytokine Release after Multiple Trauma in Mice
por: Homeier, Jil-Madeline, et al.
Publicado: (2021)

Fracture Healing in Elderly Mice and the Effect of an Additional Severe Blood Loss: A Radiographic and Biomechanical Murine Study
por: Bundkirchen, Katrin, et al.
Publicado: (2023)

Endogenous Uteroglobin as Intrinsic Anti-inflammatory Signal Modulates Monocyte and Macrophage Subsets Distribution Upon Sepsis Induced Lung Injury
por: Janicova, Andrea, et al.
Publicado: (2019)

Epidemiology of complete knee dislocations: an updated classification system
por: Mühlenfeld, Nils, et al.
Publicado: (2021)

Regulatory T Cells Modulate CD4 Proliferation after Severe Trauma via IL-10
por: Sturm, Ramona, et al.
Publicado: (2020)

The sequence of the treatment of combined fractures of the pelvis, spine, and extremities in polytraumatized patients
por: Schindler, Cora Rebecca, et al.
Publicado: (2023)

Chronic alcohol exposure increases ganglia endogenous morphine levels
por: Zhu, Wei, et al.
Publicado: (2010)

Impaired Surface Expression of HLA-DR, TLR2, TLR4, and TLR9 in Ex Vivo-In Vitro Stimulated Monocytes from Severely Injured Trauma Patients
por: Heftrig, David, et al.
Publicado: (2017)

Effects of Circulating HMGB-1 and Histones on Cardiomyocytes–Hemadsorption of These DAMPs as Therapeutic Strategy after Multiple Trauma
por: Weber, Birte, et al.
Publicado: (2020)

Visualization of complicated fractures by 3D-printed models for teaching and surgery: hands-on transitional fractures of the ankle
por: Neijhoft, Jonas, et al.
Publicado: (2022)

Who, When, Why?—Traumatological Patients in the Emergency Department of a Maximum Care Provider
por: Hörauf, Jason-Alexander, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_alf61kvouti9e6p499pablnmj1