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Objective, domain-specific HER2 measurement in uterine and ovarian serous carcinomas and its clinical significance
INTRODUCTION: HER2 overexpression/amplification is identified in up to 40% of uterine serous carcinomas (USC) and 10% of ovarian serous carcinomas (OSC). However, clinical trials using various HER2-targeted agents failed to show significant responses. FDA-approved HER2 assays target only the protein...
Autores principales: | Carvajal-Hausdorf, Daniel E., Schalper, Kurt A., Bai, Yalai, Black, Jonathan, Santin, Alessandro D., Rimm, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941302/ https://www.ncbi.nlm.nih.gov/pubmed/28196634 http://dx.doi.org/10.1016/j.ygyno.2017.02.002 |
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