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A genome-wide survey of mutations in the Jurkat cell line

BACKGROUND: The Jurkat cell line has an extensive history as a model of T cell signaling. But at the turn of the 21st century, some expression irregularities were observed, raising doubts about how closely the cell line paralleled normal human T cells. While numerous expression deficiencies have bee...

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Detalles Bibliográficos
Autores principales: Gioia, Louis, Siddique, Azeem, Head, Steven R., Salomon, Daniel R., Su, Andrew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941560/
https://www.ncbi.nlm.nih.gov/pubmed/29739316
http://dx.doi.org/10.1186/s12864-018-4718-6