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A genome-wide survey of mutations in the Jurkat cell line
BACKGROUND: The Jurkat cell line has an extensive history as a model of T cell signaling. But at the turn of the 21st century, some expression irregularities were observed, raising doubts about how closely the cell line paralleled normal human T cells. While numerous expression deficiencies have bee...
Autores principales: | Gioia, Louis, Siddique, Azeem, Head, Steven R., Salomon, Daniel R., Su, Andrew I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941560/ https://www.ncbi.nlm.nih.gov/pubmed/29739316 http://dx.doi.org/10.1186/s12864-018-4718-6 |
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