DNA methylation in the APOE genomic region is associated with cognitive function in African Americans

BACKGROUND: Genetic variations in apolipoprotein E (APOE) and proximal genes (PVRL2, TOMM40, and APOC1) are associated with cognitive function and dementia, particularly Alzheimer’s disease. Epigenetic mechanisms such as DNA methylation play a central role in the regulation of gene expression. Recen...

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Detalles Bibliográficos
Autores principales: Liu, Jiaxuan, Zhao, Wei, Ware, Erin B., Turner, Stephen T., Mosley, Thomas H., Smith, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941603/
https://www.ncbi.nlm.nih.gov/pubmed/29739406
http://dx.doi.org/10.1186/s12920-018-0363-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941603/
https://www.ncbi.nlm.nih.gov/pubmed/29739406
http://dx.doi.org/10.1186/s12920-018-0363-9

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