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M1 macrophage recruitment correlates with worse outcome in SHH Medulloblastomas

BACKGROUND: Recent progress in molecular analysis has advanced the understanding of medulloblastoma (MB) and is anticipated to facilitate management of the disease. MB is composed of 4 molecular subgroups: WNT, SHH, Group 3, and Group 4. Macrophages play a crucial role in the tumor microenvironment;...

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Detalles Bibliográficos
Autores principales: Lee, Chanhee, Lee, Joongyub, Choi, Seung Ah, Kim, Seung-Ki, Wang, Kyu-Chang, Park, Sung-Hye, Kim, Se Hoon, Lee, Ji Yeoun, Phi, Ji Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941618/
https://www.ncbi.nlm.nih.gov/pubmed/29739450
http://dx.doi.org/10.1186/s12885-018-4457-8