The role of HIV Tat protein in HIV-related cardiovascular diseases

The human immunodeficiency virus (HIV) is a major global public health issue. HIV-related cardiovascular disease remains a leading cause of morbidity and mortality in HIV positive patients. HIV Tat is a regulatory protein encoded by tat gene of HIV-1, which not only promotes the transcription of HIV...

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Autores principales: Jiang, Yanan, Chai, Lu, Fasae, Moyondafoluwa Blessing, Bai, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941636/
https://www.ncbi.nlm.nih.gov/pubmed/29739413
http://dx.doi.org/10.1186/s12967-018-1500-0
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author Jiang, Yanan
Chai, Lu
Fasae, Moyondafoluwa Blessing
Bai, Yunlong
author_facet Jiang, Yanan
Chai, Lu
Fasae, Moyondafoluwa Blessing
Bai, Yunlong
author_sort Jiang, Yanan
collection PubMed
description The human immunodeficiency virus (HIV) is a major global public health issue. HIV-related cardiovascular disease remains a leading cause of morbidity and mortality in HIV positive patients. HIV Tat is a regulatory protein encoded by tat gene of HIV-1, which not only promotes the transcription of HIV, but it is also involved in the pathogenesis of HIV-related complications. This review is aimed at summarizing the current understanding of Tat in HIV-related cardiovascular diseases.
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spelling pubmed-59416362018-05-14 The role of HIV Tat protein in HIV-related cardiovascular diseases Jiang, Yanan Chai, Lu Fasae, Moyondafoluwa Blessing Bai, Yunlong J Transl Med Review The human immunodeficiency virus (HIV) is a major global public health issue. HIV-related cardiovascular disease remains a leading cause of morbidity and mortality in HIV positive patients. HIV Tat is a regulatory protein encoded by tat gene of HIV-1, which not only promotes the transcription of HIV, but it is also involved in the pathogenesis of HIV-related complications. This review is aimed at summarizing the current understanding of Tat in HIV-related cardiovascular diseases. BioMed Central 2018-05-08 /pmc/articles/PMC5941636/ /pubmed/29739413 http://dx.doi.org/10.1186/s12967-018-1500-0 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Jiang, Yanan
Chai, Lu
Fasae, Moyondafoluwa Blessing
Bai, Yunlong
The role of HIV Tat protein in HIV-related cardiovascular diseases
title The role of HIV Tat protein in HIV-related cardiovascular diseases
title_full The role of HIV Tat protein in HIV-related cardiovascular diseases
title_fullStr The role of HIV Tat protein in HIV-related cardiovascular diseases
title_full_unstemmed The role of HIV Tat protein in HIV-related cardiovascular diseases
title_short The role of HIV Tat protein in HIV-related cardiovascular diseases
title_sort role of hiv tat protein in hiv-related cardiovascular diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941636/
https://www.ncbi.nlm.nih.gov/pubmed/29739413
http://dx.doi.org/10.1186/s12967-018-1500-0
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