Experimental infection of grey partridges with Bagaza virus: pathogenicity evaluation and potential role as a competent host

Bagaza virus (BAGV; synonymous to Israel turkey meningoencephalomyelitis virus, ITV) is a relevant arthropod-borne epornitic flavivirus. In its first emergence in Europe (southern Spain, 2010) BAGV caused an outbreak, severely affecting red-legged partridges and common pheasants. The effects (pathog...

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Autores principales: Cano-Gómez, Cristina, Llorente, Francisco, Pérez-Ramírez, Elisa, Soriguer, Ramón C., Sarasa, Mathieu, Jiménez-Clavero, Miguel Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941787/
https://www.ncbi.nlm.nih.gov/pubmed/29739470
http://dx.doi.org/10.1186/s13567-018-0536-8
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author Cano-Gómez, Cristina
Llorente, Francisco
Pérez-Ramírez, Elisa
Soriguer, Ramón C.
Sarasa, Mathieu
Jiménez-Clavero, Miguel Ángel
author_facet Cano-Gómez, Cristina
Llorente, Francisco
Pérez-Ramírez, Elisa
Soriguer, Ramón C.
Sarasa, Mathieu
Jiménez-Clavero, Miguel Ángel
author_sort Cano-Gómez, Cristina
collection PubMed
description Bagaza virus (BAGV; synonymous to Israel turkey meningoencephalomyelitis virus, ITV) is a relevant arthropod-borne epornitic flavivirus. In its first emergence in Europe (southern Spain, 2010) BAGV caused an outbreak, severely affecting red-legged partridges and common pheasants. The effects (pathogenicity, role as reservoir host) of BAGV in other European phasianids are unknown. To fill this gap, grey partridges were experimentally infected with BAGV. The clinical course of the disease was severe, with neurological signs, significant weight loss and 40% mortality. Low viral loads in the blood and the absence of contact transmission suggest a limited—if any—role on BAGV transmission for this European phasianid.
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spelling pubmed-59417872018-05-14 Experimental infection of grey partridges with Bagaza virus: pathogenicity evaluation and potential role as a competent host Cano-Gómez, Cristina Llorente, Francisco Pérez-Ramírez, Elisa Soriguer, Ramón C. Sarasa, Mathieu Jiménez-Clavero, Miguel Ángel Vet Res Short Report Bagaza virus (BAGV; synonymous to Israel turkey meningoencephalomyelitis virus, ITV) is a relevant arthropod-borne epornitic flavivirus. In its first emergence in Europe (southern Spain, 2010) BAGV caused an outbreak, severely affecting red-legged partridges and common pheasants. The effects (pathogenicity, role as reservoir host) of BAGV in other European phasianids are unknown. To fill this gap, grey partridges were experimentally infected with BAGV. The clinical course of the disease was severe, with neurological signs, significant weight loss and 40% mortality. Low viral loads in the blood and the absence of contact transmission suggest a limited—if any—role on BAGV transmission for this European phasianid. BioMed Central 2018-05-09 2018 /pmc/articles/PMC5941787/ /pubmed/29739470 http://dx.doi.org/10.1186/s13567-018-0536-8 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Report
Cano-Gómez, Cristina
Llorente, Francisco
Pérez-Ramírez, Elisa
Soriguer, Ramón C.
Sarasa, Mathieu
Jiménez-Clavero, Miguel Ángel
Experimental infection of grey partridges with Bagaza virus: pathogenicity evaluation and potential role as a competent host
title Experimental infection of grey partridges with Bagaza virus: pathogenicity evaluation and potential role as a competent host
title_full Experimental infection of grey partridges with Bagaza virus: pathogenicity evaluation and potential role as a competent host
title_fullStr Experimental infection of grey partridges with Bagaza virus: pathogenicity evaluation and potential role as a competent host
title_full_unstemmed Experimental infection of grey partridges with Bagaza virus: pathogenicity evaluation and potential role as a competent host
title_short Experimental infection of grey partridges with Bagaza virus: pathogenicity evaluation and potential role as a competent host
title_sort experimental infection of grey partridges with bagaza virus: pathogenicity evaluation and potential role as a competent host
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941787/
https://www.ncbi.nlm.nih.gov/pubmed/29739470
http://dx.doi.org/10.1186/s13567-018-0536-8
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