Cargando…

Gene Expression Profiling in Behcet's Disease Indicates an Autoimmune Component in the Pathogenesis of the Disease and Opens New Avenues for Targeted Therapy

Behçet disease (BD) is a chronic inflammatory multisystem disease characterized by oral and genital ulcers, uveitis, and skin lesions. Disease etiopathogenesis is still unclear. We aim to elucidate some aspects of BD pathogenesis and to identify specific gene signatures in peripheral blood cells (PB...

Descripción completa

Detalles Bibliográficos
Autores principales:	Puccetti, Antonio, Fiore, Piera Filomena, Pelosi, Andrea, Tinazzi, Elisa, Patuzzo, Giuseppe, Argentino, Giuseppe, Moretta, Francesca, Lunardi, Claudio, Dolcino, Marzia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941805/ https://www.ncbi.nlm.nih.gov/pubmed/29850627 http://dx.doi.org/10.1155/2018/4246965

Ejemplares similares

MicroRNA Expression Profiling in Behçet's Disease
por: Puccetti, Antonio, et al.
Publicado: (2018)

MicroRNA Expression Profiling in Psoriatic Arthritis
por: Pelosi, Andrea, et al.
Publicado: (2018)

Long Non-Coding RNAs Play a Role in the Pathogenesis of Psoriatic Arthritis by Regulating MicroRNAs and Genes Involved in Inflammation and Metabolic Syndrome
por: Dolcino, Marzia, et al.
Publicado: (2018)

Gene Profiling in Patients with Systemic Sclerosis Reveals the Presence of Oncogenic Gene Signatures
por: Dolcino, Marzia, et al.
Publicado: (2018)

Gene Expression Profiling in Fibromyalgia Indicates an Autoimmune Origin of the Disease and Opens New Avenues for Targeted Therapy
por: Dolcino, Marzia, et al.
Publicado: (2020)

Gene Expression Analysis before and after Treatment with Adalimumab in Patients with Ankylosing Spondylitis Identifies Molecular Pathways Associated with Response to Therapy
por: Dolcino, Marzia, et al.
Publicado: (2017)

Gene Expression Profiling in Peripheral Blood Cells and Synovial Membranes of Patients with Psoriatic Arthritis
por: Dolcino, Marzia, et al.
Publicado: (2015)

Gene Expression Profiling in Peripheral Blood Mononuclear Cells of Patients with Common Variable Immunodeficiency: Modulation of Adaptive Immune Response following Intravenous Immunoglobulin Therapy
por: Dolcino, Marzia, et al.
Publicado: (2014)

Characterization of CD30/CD30L(+) Cells in Peripheral Blood and Synovial Fluid of Patients with Rheumatoid Arthritis
por: Barbieri, Alessandro, et al.
Publicado: (2015)

Endothelin Receptors Expressed by Immune Cells Are Involved in Modulation of Inflammation and in Fibrosis: Relevance to the Pathogenesis of Systemic Sclerosis
por: Elisa, Tinazzi, et al.
Publicado: (2015)

Crossreactive Autoantibodies Directed against Cutaneous and Joint Antigens Are Present in Psoriatic Arthritis
por: Dolcino, Marzia, et al.
Publicado: (2014)

In Systemic Sclerosis, a Unique Long Non Coding RNA Regulates Genes and Pathways Involved in the Three Main Features of the Disease (Vasculopathy, Fibrosis and Autoimmunity) and in Carcinogenesis
por: Dolcino, Marzia, et al.
Publicado: (2019)

Long Non-Coding RNAs Modulate Sjögren’s Syndrome Associated Gene Expression and Are Involved in the Pathogenesis of the Disease
por: Dolcino, Marzia, et al.
Publicado: (2019)

Immune Response to Rotavirus and Gluten Sensitivity
por: Puccetti, Antonio, et al.
Publicado: (2018)

Long Non-Coding RNAs Target Pathogenetically Relevant Genes and Pathways in Rheumatoid Arthritis
por: Dolcino, Marzia, et al.
Publicado: (2019)

Antibodies Directed against a Peptide Epitope of a Klebsiella pneumoniae-Derived Protein Are Present in Ankylosing Spondylitis
por: Puccetti, Antonio, et al.
Publicado: (2017)

Editorial: Role of Epigenetics in Autoimmune Diseases
por: Dolcino, Marzia, et al.
Publicado: (2020)

Endothelial Cells' Activation and Apoptosis Induced by a Subset of Antibodies against Human Cytomegalovirus: Relevance to the Pathogenesis of Atherosclerosis
por: Lunardi, Claudio, et al.
Publicado: (2007)

Gene expression profiling in circulating endothelial cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis that is modified by iloprost infusion
por: Tinazzi, Elisa, et al.
Publicado: (2010)

Profibrotic Effects of Endothelin-1 on Fibroblasts Are Mediated by Aldosterone In Vitro: Relevance to the Pathogenesis and Therapy of Systemic Sclerosis and Pulmonary Arterial Hypertension
por: Argentino, Giuseppe, et al.
Publicado: (2022)

Gene Expression Profiling in Dermatitis Herpetiformis Skin Lesions
por: Dolcino, M., et al.
Publicado: (2012)

Antibodies against Human Cytomegalovirus in the Pathogenesis of Systemic Sclerosis: A Gene Array Approach
por: Lunardi, Claudio, et al.
Publicado: (2006)

Identification of a Novel Serological Marker in Seronegative Rheumatoid Arthritis Using the Peptide Library Approach
por: Bason, Caterina, et al.
Publicado: (2021)

In Celiac Disease, a Subset of Autoantibodies against Transglutaminase Binds Toll-Like Receptor 4 and Induces Activation of Monocytes
por: Zanoni, Giovanna, et al.
Publicado: (2006)

In Type 1 Diabetes a Subset of Anti-Coxsackievirus B4 Antibodies Recognize Autoantigens and Induce Apoptosis of Pancreatic Beta Cells
por: Bason, Caterina, et al.
Publicado: (2013)

Behçet’s Disease: Autoimmune or Autoinflammatory?
por: Hedayatfar, Alireza
Publicado: (2013)

Gene Expression Profiles in Primary Sjögren's Syndrome With and Without Systemic Manifestations
por: Vitali, Claudio, et al.
Publicado: (2019)

Streptococcal antigen in the pathogenesis of Behçet's disease
por: Kaneko, F, et al.
Publicado: (2003)

The Role of Th17 Cells in the Pathogenesis of Behcet’s Disease
por: Nanke, Yuki, et al.
Publicado: (2017)

Behçet’s Disease—Do Microbiomes and Genetics Collaborate in Pathogenesis?
por: Mehmood, Nafeesa, et al.
Publicado: (2021)

Advances in pathogenesis and treatment of ocular involvement in Behcet’s disease
por: Lin, Suibin, et al.
Publicado: (2023)

Thyroid Autoimmunity and Behçet's Disease: Is There a Significant Association?
por: Cebeci, Filiz, et al.
Publicado: (2013)

Behçet's Disease (Adamantiades-Behçet's Disease)
por: Kaneko, Fumio, et al.
Publicado: (2011)

Osteoporosis pathogenesis and treatment: existing and emerging avenues
por: Liang, Bo, et al.
Publicado: (2022)

Homocysteine May Involve in the Pathogenesis of Behcet's Disease by Inducing Inflammation
por: Kartal Durmazlar, Selda Pelin, et al.
Publicado: (2008)

Pathogenesis of autoimmune disease
por: Pisetsky, David S.
Publicado: (2023)

Editorial: The Immunology of Sepsis—Understanding Host Susceptibility, Pathogenesis of Disease, and Avenues for Future Treatment
por: Schlapbach, Luregn J., et al.
Publicado: (2020)

Autoimmune sensorineural hearing loss as presenting manifestation of paediatric Behçet disease responding to adalimumab: a case report
por: Marsili, Manuela, et al.
Publicado: (2016)

MicroRNA analysis of Natural Killer cell-derived exosomes: the microRNA let-7b-5p is enriched in exosomes and participates in their anti-tumor effects against pancreatic cancer cells
por: Di Pace, Anna Laura, et al.
Publicado: (2023)

Critical Role of Gut Microbiota and Epigenetic Factors in the Pathogenesis of Behçet’s Disease
por: Ma, Xiaomin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_eusa2ebmscjkt5uj2ae5dtj3gg