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Randomised controlled trial of high versus ad libitum water intake in patients with autosomal dominant polycystic kidney disease: rationale and design of the DRINK feasibility trial

INTRODUCTION: Vasopressin stimulates cyst growth in autosomal dominant polycystic kidney disease (ADPKD) leading to enlarged kidneys, hypertension and renal failure. Vasopressin receptor blockade slows disease progression. Physiological suppression of vasopressin secretion through high water (HW) in...

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Detalles Bibliográficos
Autores principales:	El-Damanawi, Ragada, Lee, Michael, Harris, Tess, Mader, Laura B, Bond, Simon, Pavey, Holly, Sandford, Richard N, Wilkinson, Ian B, Burrows, Alison, Woznowski, Przemyslaw, Ben-Shlomo, Yoav, Karet Frankl, Fiona E, Hiemstra, Thomas F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2018
Materias:	Renal Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942404/ https://www.ncbi.nlm.nih.gov/pubmed/29743334 http://dx.doi.org/10.1136/bmjopen-2018-022859

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