Simultaneous lineage tracing and cell-type identification using CRISPR/Cas9-induced genetic scars

A key goal of developmental biology is to understand how a single cell transforms into a full-grown organism comprising many different cell types. Single-cell RNA-sequencing (scRNA-seq) is commonly used to identify cell types in a tissue or organ1. However, organizing the resulting taxonomy of cell...

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Detalles Bibliográficos
Autores principales: Spanjaard, Bastiaan, Hu, Bo, Mitic, Nina, Olivares-Chauvet, Pedro, Janjuha, Sharan, Ninov, Nikolay, Junker, Jan Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942543/
https://www.ncbi.nlm.nih.gov/pubmed/29644996
http://dx.doi.org/10.1038/nbt.4124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942543/
https://www.ncbi.nlm.nih.gov/pubmed/29644996
http://dx.doi.org/10.1038/nbt.4124

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