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Increased α-actinin-1 destabilizes E-cadherin-based adhesions and associates with poor prognosis in basal-like breast cancer

The controlled formation and stabilization of E-cadherin-based adhesions is vital for epithelial integrity. This requires co-operation between the E-cadherin-based adhesions and the associated actin cytoskeleton. In cancer, this co-operation often fails, predisposing cells to migration through molec...

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Detalles Bibliográficos
Autores principales:	Kovac, Bianca, Mäkelä, Tomi P., Vallenius, Tea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942811/ https://www.ncbi.nlm.nih.gov/pubmed/29742177 http://dx.doi.org/10.1371/journal.pone.0196986

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