Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer

This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population. A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR....

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Detalles Bibliográficos
Autores principales: Chen, Xiang-ru, Dong, Jia-nan, Zhang, Fan, Yao, Tian-ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943132/
https://www.ncbi.nlm.nih.gov/pubmed/29505510
http://dx.doi.org/10.1097/MD.0000000000009243
Descripción
Sumario:This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population. A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes included complete response (CR), partial response (PR), stable disease (SD), progress disease (PD), overall response rate (ORR), and overall survival (OS). In addition, toxicities were also recorded in this study. Three-year CR, PR, SD, PD, ORR, and OS were 47.6%, 38.1%, 9.5%, 4.8%, 85.7%, and 48.0 months, respectively. Additionally, mild toxicities were found in this study. This study demonstrated that IGSBR is efficacious for patients with stage I lung cancer with mild toxicities among Chinese Han population.

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