Cargando…

Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer

This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population. A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR....

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xiang-ru, Dong, Jia-nan, Zhang, Fan, Yao, Tian-ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943132/
https://www.ncbi.nlm.nih.gov/pubmed/29505510
http://dx.doi.org/10.1097/MD.0000000000009243
_version_ 1783321578232086528
author Chen, Xiang-ru
Dong, Jia-nan
Zhang, Fan
Yao, Tian-ling
author_facet Chen, Xiang-ru
Dong, Jia-nan
Zhang, Fan
Yao, Tian-ling
author_sort Chen, Xiang-ru
collection PubMed
description This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population. A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes included complete response (CR), partial response (PR), stable disease (SD), progress disease (PD), overall response rate (ORR), and overall survival (OS). In addition, toxicities were also recorded in this study. Three-year CR, PR, SD, PD, ORR, and OS were 47.6%, 38.1%, 9.5%, 4.8%, 85.7%, and 48.0 months, respectively. Additionally, mild toxicities were found in this study. This study demonstrated that IGSBR is efficacious for patients with stage I lung cancer with mild toxicities among Chinese Han population.
format Online
Article
Text
id pubmed-5943132
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Wolters Kluwer Health
record_format MEDLINE/PubMed
spelling pubmed-59431322018-05-15 Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer Chen, Xiang-ru Dong, Jia-nan Zhang, Fan Yao, Tian-ling Medicine (Baltimore) Research Article This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population. A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes included complete response (CR), partial response (PR), stable disease (SD), progress disease (PD), overall response rate (ORR), and overall survival (OS). In addition, toxicities were also recorded in this study. Three-year CR, PR, SD, PD, ORR, and OS were 47.6%, 38.1%, 9.5%, 4.8%, 85.7%, and 48.0 months, respectively. Additionally, mild toxicities were found in this study. This study demonstrated that IGSBR is efficacious for patients with stage I lung cancer with mild toxicities among Chinese Han population. Wolters Kluwer Health 2018-01-05 /pmc/articles/PMC5943132/ /pubmed/29505510 http://dx.doi.org/10.1097/MD.0000000000009243 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-nc-sa/4.0
spellingShingle Research Article
Chen, Xiang-ru
Dong, Jia-nan
Zhang, Fan
Yao, Tian-ling
Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer
title Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer
title_full Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer
title_fullStr Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer
title_full_unstemmed Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer
title_short Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer
title_sort efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943132/
https://www.ncbi.nlm.nih.gov/pubmed/29505510
http://dx.doi.org/10.1097/MD.0000000000009243
work_keys_str_mv AT chenxiangru efficacyandsafetyofimageguidanceradiotherapybyhelicaltomotherapyinpatientswithlungcancer
AT dongjianan efficacyandsafetyofimageguidanceradiotherapybyhelicaltomotherapyinpatientswithlungcancer
AT zhangfan efficacyandsafetyofimageguidanceradiotherapybyhelicaltomotherapyinpatientswithlungcancer
AT yaotianling efficacyandsafetyofimageguidanceradiotherapybyhelicaltomotherapyinpatientswithlungcancer