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Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer
This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population. A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943132/ https://www.ncbi.nlm.nih.gov/pubmed/29505510 http://dx.doi.org/10.1097/MD.0000000000009243 |
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author | Chen, Xiang-ru Dong, Jia-nan Zhang, Fan Yao, Tian-ling |
author_facet | Chen, Xiang-ru Dong, Jia-nan Zhang, Fan Yao, Tian-ling |
author_sort | Chen, Xiang-ru |
collection | PubMed |
description | This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population. A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes included complete response (CR), partial response (PR), stable disease (SD), progress disease (PD), overall response rate (ORR), and overall survival (OS). In addition, toxicities were also recorded in this study. Three-year CR, PR, SD, PD, ORR, and OS were 47.6%, 38.1%, 9.5%, 4.8%, 85.7%, and 48.0 months, respectively. Additionally, mild toxicities were found in this study. This study demonstrated that IGSBR is efficacious for patients with stage I lung cancer with mild toxicities among Chinese Han population. |
format | Online Article Text |
id | pubmed-5943132 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-59431322018-05-15 Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer Chen, Xiang-ru Dong, Jia-nan Zhang, Fan Yao, Tian-ling Medicine (Baltimore) Research Article This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population. A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes included complete response (CR), partial response (PR), stable disease (SD), progress disease (PD), overall response rate (ORR), and overall survival (OS). In addition, toxicities were also recorded in this study. Three-year CR, PR, SD, PD, ORR, and OS were 47.6%, 38.1%, 9.5%, 4.8%, 85.7%, and 48.0 months, respectively. Additionally, mild toxicities were found in this study. This study demonstrated that IGSBR is efficacious for patients with stage I lung cancer with mild toxicities among Chinese Han population. Wolters Kluwer Health 2018-01-05 /pmc/articles/PMC5943132/ /pubmed/29505510 http://dx.doi.org/10.1097/MD.0000000000009243 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-nc-sa/4.0 |
spellingShingle | Research Article Chen, Xiang-ru Dong, Jia-nan Zhang, Fan Yao, Tian-ling Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer |
title | Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer |
title_full | Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer |
title_fullStr | Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer |
title_full_unstemmed | Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer |
title_short | Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer |
title_sort | efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943132/ https://www.ncbi.nlm.nih.gov/pubmed/29505510 http://dx.doi.org/10.1097/MD.0000000000009243 |
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