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Auto-FPFA: An Automated Microscope for Characterizing Genetically Encoded Biosensors

Genetically encoded biosensors function by linking structural change in a protein construct, typically tagged with one or more fluorescent proteins, to changes in a biological parameter of interest (such as calcium concentration, pH, phosphorylation-state, etc.). Typically, the structural change tri...

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Detalles Bibliográficos
Autores principales: Nguyen, Tuan A., Puhl, Henry L., Pham, An K., Vogel, Steven S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943267/
https://www.ncbi.nlm.nih.gov/pubmed/29743504
http://dx.doi.org/10.1038/s41598-018-25689-x