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Isozyme-specific comprehensive characterization of transglutaminase-crosslinked substrates in kidney fibrosis
Chronic kidney disease is characterized by prolonged decline in renal function, excessive accumulation of ECM, and progressive tissue fibrosis. Transglutaminase (TG) is a crosslinking enzyme that catalyzes the formation of covalent bonds between glutamine and lysine residues, and is involved in the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943318/ https://www.ncbi.nlm.nih.gov/pubmed/29743665 http://dx.doi.org/10.1038/s41598-018-25674-4 |