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Isozyme-specific comprehensive characterization of transglutaminase-crosslinked substrates in kidney fibrosis

Chronic kidney disease is characterized by prolonged decline in renal function, excessive accumulation of ECM, and progressive tissue fibrosis. Transglutaminase (TG) is a crosslinking enzyme that catalyzes the formation of covalent bonds between glutamine and lysine residues, and is involved in the...

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Detalles Bibliográficos
Autores principales:	Tatsukawa, Hideki, Otsu, Risa, Tani, Yuji, Wakita, Ryosuke, Hitomi, Kiyotaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943318/ https://www.ncbi.nlm.nih.gov/pubmed/29743665 http://dx.doi.org/10.1038/s41598-018-25674-4

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