A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

Malaria liver stages represent an ideal therapeutic target with a bottleneck in parasite load and reduced clinical symptoms; however, current in vitro pre-erythrocytic (PE) models for Plasmodium vivax and P. falciparum lack the efficiency necessary for rapid identification and effective evaluation o...

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Detalles Bibliográficos
Autores principales: Roth, Alison, Maher, Steven P., Conway, Amy J., Ubalee, Ratawan, Chaumeau, Victor, Andolina, Chiara, Kaba, Stephen A., Vantaux, Amélie, Bakowski, Malina A., Thomson-Luque, Richard, Adapa, Swamy Rakesh, Singh, Naresh, Barnes, Samantha J., Cooper, Caitlin A., Rouillier, Mélanie, McNamara, Case W., Mikolajczak, Sebastian A., Sather, Noah, Witkowski, Benoît, Campo, Brice, Kappe, Stefan H. I., Lanar, David E., Nosten, François, Davidson, Silas, Jiang, Rays H. Y., Kyle, Dennis E., Adams, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943321/
https://www.ncbi.nlm.nih.gov/pubmed/29743474
http://dx.doi.org/10.1038/s41467-018-04221-9

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