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Trivalent soluble TNF Receptor, a potent TNF-α antagonist for the treatment collagen-induced arthritis
Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target for intervening autoimmune diseases such as rheumatoid arthritis and psoriasis. However, cur...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943350/ https://www.ncbi.nlm.nih.gov/pubmed/29743640 http://dx.doi.org/10.1038/s41598-018-25652-w |