Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer

PP2A is a major tumor suppressor whose inactivation is frequently found in a wide spectrum of human tumors. In particular, deletion or epigenetic silencing of genes encoding the B55 family of PP2A regulatory subunits is a common feature of breast cancer cells. A key player in the regulation of PP2A/...

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Detalles Bibliográficos
Autores principales: Álvarez-Fernández, Mónica, Sanz-Flores, María, Sanz-Castillo, Belén, Salazar-Roa, María, Partida, David, Zapatero-Solana, Elisabet, Ali, H. Raza, Manchado, Eusebio, Lowe, Scott, VanArsdale, Todd, Shields, David, Caldas, Carlos, Quintela-Fandino, Miguel, Malumbres, Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943447/
https://www.ncbi.nlm.nih.gov/pubmed/29229993
http://dx.doi.org/10.1038/s41418-017-0024-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943447/
https://www.ncbi.nlm.nih.gov/pubmed/29229993
http://dx.doi.org/10.1038/s41418-017-0024-0

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