Antibiotic‐mediated bacteriome depletion in Apc(Min/+) mice is associated with reduction in mucus‐producing goblet cells and increased colorectal cancer progression

Recent epidemiological evidence suggests that exposure to antibiotics in early‐to‐middle adulthood is associated with an increased risk of colorectal adenoma. However, mechanistic studies in established preclinical cancer to examine these claims are extremely limited. Therefore, we investigated the...

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Detalles Bibliográficos
Autores principales: Kaur, Kamaljeet, Saxena, Arpit, Debnath, Irina, O'Brien, Jacqueline L., Ajami, Nadim J., Auchtung, Thomas A., Petrosino, Joseph F., Sougiannis, Alexander‐Jacques, Depaep, Sarah, Chumanevich, Alexander, Gummadidala, Phani M., Omebeyinje, Mayomi H., Banerjee, Sourav, Chatzistamou, Ioulia, Chakraborty, Paramita, Fayad, Raja, Berger, Franklin G., Carson, James A., Chanda, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943478/
https://www.ncbi.nlm.nih.gov/pubmed/29624892
http://dx.doi.org/10.1002/cam4.1460

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