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Co-Stimulation-Impaired Bone Marrow-Derived Dendritic Cells Prevent Dextran Sodium Sulfate-Induced Colitis in Mice

Dendritic cells (DC) are important in the onset and severity of inflammatory bowel disease (IBD). Tolerogenic DC induce T-cells to become therapeutic Foxp3+ regulatory T-cells (Tregs). We therefore asked if experimental IBD could be prevented by administration of bone marrow-derived DC generated und...

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Detalles Bibliográficos
Autores principales:	Engman, Carl, Garciafigueroa, Yesica, Phillips, Brett Eugene, Trucco, Massimo, Giannoukakis, Nick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943510/ https://www.ncbi.nlm.nih.gov/pubmed/29774025 http://dx.doi.org/10.3389/fimmu.2018.00894

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