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Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum

The caudal region of the rodent striatum, called the tail of the striatum (TS), is a relatively small area but might have a distinct function from other striatal subregions. Recent primate studies showed that this part of the striatum has a unique function in encoding long-term value memory of visua...

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Autores principales: Jiang, Haiyan, Kim, Hyoung F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943565/
https://www.ncbi.nlm.nih.gov/pubmed/29773980
http://dx.doi.org/10.3389/fnana.2018.00030
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author Jiang, Haiyan
Kim, Hyoung F.
author_facet Jiang, Haiyan
Kim, Hyoung F.
author_sort Jiang, Haiyan
collection PubMed
description The caudal region of the rodent striatum, called the tail of the striatum (TS), is a relatively small area but might have a distinct function from other striatal subregions. Recent primate studies showed that this part of the striatum has a unique function in encoding long-term value memory of visual objects for habitual behavior. This function might be due to its specific connectivity. We identified inputs to the rat TS and compared those with inputs to the dorsomedial striatum (DMS) in the same animals. The TS directly received anatomical inputs from both sensory structures and value-coding regions, but the DMS did not. First, inputs from the sensory cortex and sensory thalamus to the TS were found; visual, auditory, somatosensory and gustatory cortex and thalamus projected to the TS but not to the DMS. Second, two value systems innervated the TS; dopamine and serotonin neurons in the lateral part of the substantia nigra pars compacta (SNc) and dorsal raphe nucleus projected to the TS, respectively. The DMS received inputs from the separate group of dopamine neurons in the medial part of the SNc. In addition, learning-related regions of the limbic system innervated the TS; the temporal areas and the basolateral amygdala selectively innervated the TS, but not the DMS. Our data showed that both sensory and value-processing structures innervated the TS, suggesting its plausible role in value-guided sensory-motor association for habitual behavior.
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spelling pubmed-59435652018-05-17 Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum Jiang, Haiyan Kim, Hyoung F. Front Neuroanat Neuroscience The caudal region of the rodent striatum, called the tail of the striatum (TS), is a relatively small area but might have a distinct function from other striatal subregions. Recent primate studies showed that this part of the striatum has a unique function in encoding long-term value memory of visual objects for habitual behavior. This function might be due to its specific connectivity. We identified inputs to the rat TS and compared those with inputs to the dorsomedial striatum (DMS) in the same animals. The TS directly received anatomical inputs from both sensory structures and value-coding regions, but the DMS did not. First, inputs from the sensory cortex and sensory thalamus to the TS were found; visual, auditory, somatosensory and gustatory cortex and thalamus projected to the TS but not to the DMS. Second, two value systems innervated the TS; dopamine and serotonin neurons in the lateral part of the substantia nigra pars compacta (SNc) and dorsal raphe nucleus projected to the TS, respectively. The DMS received inputs from the separate group of dopamine neurons in the medial part of the SNc. In addition, learning-related regions of the limbic system innervated the TS; the temporal areas and the basolateral amygdala selectively innervated the TS, but not the DMS. Our data showed that both sensory and value-processing structures innervated the TS, suggesting its plausible role in value-guided sensory-motor association for habitual behavior. Frontiers Media S.A. 2018-05-03 /pmc/articles/PMC5943565/ /pubmed/29773980 http://dx.doi.org/10.3389/fnana.2018.00030 Text en Copyright © 2018 Jiang and Kim. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Jiang, Haiyan
Kim, Hyoung F.
Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum
title Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum
title_full Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum
title_fullStr Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum
title_full_unstemmed Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum
title_short Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum
title_sort anatomical inputs from the sensory and value structures to the tail of the rat striatum
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943565/
https://www.ncbi.nlm.nih.gov/pubmed/29773980
http://dx.doi.org/10.3389/fnana.2018.00030
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