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Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma

Several lines of evidence have demonstrated that deregulated activation of NF-κB plays a pivotal role in the initiation and progression of a variety of cancers including multiple myeloma (MM). Therefore, novel molecules that can effectively suppress deregulated NF-κB upregulation can potentially red...

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Detalles Bibliográficos
Autores principales: Shanmugam, Muthu K., Ahn, Kwang S., Lee, Jong H., Kannaiyan, Radhamani, Mustafa, Nurulhuda, Manu, Kanjoormana A., Siveen, Kodappully S., Sethi, Gautam, Chng, Wee J., Kumar, Alan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943600/
https://www.ncbi.nlm.nih.gov/pubmed/29773987
http://dx.doi.org/10.3389/fphar.2018.00365