Targeting RNS/caveolin-1/MMP signaling cascades to protect against cerebral ischemia-reperfusion injuries: potential application for drug discovery

Reactive nitrogen species (RNS) play important roles in mediating cerebral ischemia-reperfusion injury. RNS activate multiple signaling pathways and participate in different cellular events in cerebral ischemia-reperfusion injury. Recent studies have indicated that caveolin-1 and matrix metalloprote...

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Detalles Bibliográficos
Autores principales: Chen, Han-sen, Chen, Xi, Li, Wen-ting, Shen, Jian-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943912/
https://www.ncbi.nlm.nih.gov/pubmed/29595191
http://dx.doi.org/10.1038/aps.2018.27

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