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TRPM2: a candidate therapeutic target for treating neurological diseases

Transient receptor potential melastatin 2 (TRPM2) is a calcium (Ca(2+))-permeable non-selective cation channel belonging to the TRP ion channel family. Oxidative stress-induced TRPM2 activation provokes aberrant intracellular Ca(2+) accumulation and cell death in a variety of cell types, including n...

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Detalles Bibliográficos
Autores principales: Belrose, Jillian Corinne, Jackson, Michael Frederick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943913/
https://www.ncbi.nlm.nih.gov/pubmed/29671419
http://dx.doi.org/10.1038/aps.2018.31