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Ketamine exacerbates cortical neuroapoptosis under hyperoxic conditions by upregulating expression of the N-methyl-D-aspartate receptor subunit NR1 in the developing rat brain

BACKGROUND: Ketamine and hyperoxia are widely used in obstetric and pediatric settings. Either ketamine or hyperoxia has been reported to cause neuroapoptosis in the developing brain, and ketamine-induced neuronal apoptosis may involve a compensatory upregulation of the N-methyl-D-aspartate (NMDA) r...

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Detalles Bibliográficos
Autores principales:	Wu, Changyi, Wang, Jun, Guo, Xiangyang, Zhang, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944052/ https://www.ncbi.nlm.nih.gov/pubmed/29747570 http://dx.doi.org/10.1186/s12871-018-0511-y

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