Cargando…

Mycotic aneurysm caused by Edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review

BACKGROUND: Mycotic aneurysm is an uncommon disease which could be fatal without appropriate treatment. Although standard therapy for mycotic aneurysms consists of resection of the infected aorta and in situ graft replacement, some treat with endovascular stent-grafting because patients may not tole...

Descripción completa

Detalles Bibliográficos
Autores principales: Ebisawa, Kei Furui, Nishimura, Sho, Yamamoto, Shungo, Ohji, Goh, Iwata, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944098/
https://www.ncbi.nlm.nih.gov/pubmed/29747632
http://dx.doi.org/10.1186/s12941-018-0273-x
_version_ 1783321760499761152
author Ebisawa, Kei Furui
Nishimura, Sho
Yamamoto, Shungo
Ohji, Goh
Iwata, Kentaro
author_facet Ebisawa, Kei Furui
Nishimura, Sho
Yamamoto, Shungo
Ohji, Goh
Iwata, Kentaro
author_sort Ebisawa, Kei Furui
collection PubMed
description BACKGROUND: Mycotic aneurysm is an uncommon disease which could be fatal without appropriate treatment. Although standard therapy for mycotic aneurysms consists of resection of the infected aorta and in situ graft replacement, some treat with endovascular stent-grafting because patients may not tolerate graft replacement due to underlying diseases. There are 6 more reported cases of mycotic aneurysm caused by Edwardsiella tarda. With the exception of our case, all underwent resection and debridement of the infected aorta or vascular prosthesis. Herein we report the first case ever of mycotic aneurysm caused by E. tarda, successfully treated with stenting and suppressive antibiotic therapy without resection of the infected aorta. CASE PRESENTATION: A 65-year-old Japanese woman with cirrhosis and hepatocellular carcinoma complained of fatigue. Her work up revealed a ruptured aneurysm of the descending aorta. She went through endovascular stent-graft placement. Edwardsiella tarda grew from blood cultures, which led to the diagnosis of mycotic aneurysm. Edwardsiella tarda is a Gram negative bacillus which rarely causes infections in humans. In the case of bacteremia, its mortality is reported to be very high and all reported cases with mycotic aneurysm caused by E. tarda ended up with resection of the infected aorta. CONCLUSION: Our case shows that in the case of mycotic aneurysm caused by E. tarda, endovascular stent-graft placement could be an alternative to in situ graft replacement. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12941-018-0273-x) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-5944098
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-59440982018-05-14 Mycotic aneurysm caused by Edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review Ebisawa, Kei Furui Nishimura, Sho Yamamoto, Shungo Ohji, Goh Iwata, Kentaro Ann Clin Microbiol Antimicrob Case Report BACKGROUND: Mycotic aneurysm is an uncommon disease which could be fatal without appropriate treatment. Although standard therapy for mycotic aneurysms consists of resection of the infected aorta and in situ graft replacement, some treat with endovascular stent-grafting because patients may not tolerate graft replacement due to underlying diseases. There are 6 more reported cases of mycotic aneurysm caused by Edwardsiella tarda. With the exception of our case, all underwent resection and debridement of the infected aorta or vascular prosthesis. Herein we report the first case ever of mycotic aneurysm caused by E. tarda, successfully treated with stenting and suppressive antibiotic therapy without resection of the infected aorta. CASE PRESENTATION: A 65-year-old Japanese woman with cirrhosis and hepatocellular carcinoma complained of fatigue. Her work up revealed a ruptured aneurysm of the descending aorta. She went through endovascular stent-graft placement. Edwardsiella tarda grew from blood cultures, which led to the diagnosis of mycotic aneurysm. Edwardsiella tarda is a Gram negative bacillus which rarely causes infections in humans. In the case of bacteremia, its mortality is reported to be very high and all reported cases with mycotic aneurysm caused by E. tarda ended up with resection of the infected aorta. CONCLUSION: Our case shows that in the case of mycotic aneurysm caused by E. tarda, endovascular stent-graft placement could be an alternative to in situ graft replacement. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12941-018-0273-x) contains supplementary material, which is available to authorized users. BioMed Central 2018-05-10 /pmc/articles/PMC5944098/ /pubmed/29747632 http://dx.doi.org/10.1186/s12941-018-0273-x Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Ebisawa, Kei Furui
Nishimura, Sho
Yamamoto, Shungo
Ohji, Goh
Iwata, Kentaro
Mycotic aneurysm caused by Edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review
title Mycotic aneurysm caused by Edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review
title_full Mycotic aneurysm caused by Edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review
title_fullStr Mycotic aneurysm caused by Edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review
title_full_unstemmed Mycotic aneurysm caused by Edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review
title_short Mycotic aneurysm caused by Edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review
title_sort mycotic aneurysm caused by edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944098/
https://www.ncbi.nlm.nih.gov/pubmed/29747632
http://dx.doi.org/10.1186/s12941-018-0273-x
work_keys_str_mv AT ebisawakeifurui mycoticaneurysmcausedbyedwardsiellatardasuccessfullytreatedwithstentingandsuppressiveantibiotictherapyacasereportandsystematicreview
AT nishimurasho mycoticaneurysmcausedbyedwardsiellatardasuccessfullytreatedwithstentingandsuppressiveantibiotictherapyacasereportandsystematicreview
AT yamamotoshungo mycoticaneurysmcausedbyedwardsiellatardasuccessfullytreatedwithstentingandsuppressiveantibiotictherapyacasereportandsystematicreview
AT ohjigoh mycoticaneurysmcausedbyedwardsiellatardasuccessfullytreatedwithstentingandsuppressiveantibiotictherapyacasereportandsystematicreview
AT iwatakentaro mycoticaneurysmcausedbyedwardsiellatardasuccessfullytreatedwithstentingandsuppressiveantibiotictherapyacasereportandsystematicreview