Cargando…

Accelerated and enhanced osteointegration of MAO-treated implants: histological and histomorphometric evaluation in a rabbit model

Microarc oxidation (MAO) has become a promising technique for the surface modification of implants. Therefore, the aims of this study were to further quantitatively and qualitatively evaluate the osteointegration abilities of MAO-treated and smooth surface (SF) implants in vivo and to investigate th...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xin, Xu, Haiyang, Zhao, Baodong, Jiang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944253/
https://www.ncbi.nlm.nih.gov/pubmed/29563493
http://dx.doi.org/10.1038/s41368-018-0008-z
_version_ 1783321796662001664
author Li, Xin
Xu, Haiyang
Zhao, Baodong
Jiang, Shuai
author_facet Li, Xin
Xu, Haiyang
Zhao, Baodong
Jiang, Shuai
author_sort Li, Xin
collection PubMed
description Microarc oxidation (MAO) has become a promising technique for the surface modification of implants. Therefore, the aims of this study were to further quantitatively and qualitatively evaluate the osteointegration abilities of MAO-treated and smooth surface (SF) implants in vivo and to investigate the areas in which the superiority of MAO-treated implants are displayed. In a rabbit model, a comprehensive histomorphological, osteogenic, mineralizational, and integrative assessment was performed using light microscopy, fluorescence microscopy, confocal laser scanning microscopy, and radiographic analyses. Compared with the SF groups, the MAO-treated groups exhibited more active contact osteogenesis, as well as distant osteogenesis, under fluorescence examination, the mineral apposition rate was found to be greater for all of the MAO-treated implants, and the osteointegration index (OI) value was greater in the MAO-treated groups at different times. In conclusion, the calcium-rich amorphous layer created by MAO provided a better environment for osteointegration, with more active contact osteogenesis, a more rapid mineral apposition rate and greater OI values.
format Online
Article
Text
id pubmed-5944253
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-59442532018-05-11 Accelerated and enhanced osteointegration of MAO-treated implants: histological and histomorphometric evaluation in a rabbit model Li, Xin Xu, Haiyang Zhao, Baodong Jiang, Shuai Int J Oral Sci Article Microarc oxidation (MAO) has become a promising technique for the surface modification of implants. Therefore, the aims of this study were to further quantitatively and qualitatively evaluate the osteointegration abilities of MAO-treated and smooth surface (SF) implants in vivo and to investigate the areas in which the superiority of MAO-treated implants are displayed. In a rabbit model, a comprehensive histomorphological, osteogenic, mineralizational, and integrative assessment was performed using light microscopy, fluorescence microscopy, confocal laser scanning microscopy, and radiographic analyses. Compared with the SF groups, the MAO-treated groups exhibited more active contact osteogenesis, as well as distant osteogenesis, under fluorescence examination, the mineral apposition rate was found to be greater for all of the MAO-treated implants, and the osteointegration index (OI) value was greater in the MAO-treated groups at different times. In conclusion, the calcium-rich amorphous layer created by MAO provided a better environment for osteointegration, with more active contact osteogenesis, a more rapid mineral apposition rate and greater OI values. Nature Publishing Group UK 2018-03-22 /pmc/articles/PMC5944253/ /pubmed/29563493 http://dx.doi.org/10.1038/s41368-018-0008-z Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Li, Xin
Xu, Haiyang
Zhao, Baodong
Jiang, Shuai
Accelerated and enhanced osteointegration of MAO-treated implants: histological and histomorphometric evaluation in a rabbit model
title Accelerated and enhanced osteointegration of MAO-treated implants: histological and histomorphometric evaluation in a rabbit model
title_full Accelerated and enhanced osteointegration of MAO-treated implants: histological and histomorphometric evaluation in a rabbit model
title_fullStr Accelerated and enhanced osteointegration of MAO-treated implants: histological and histomorphometric evaluation in a rabbit model
title_full_unstemmed Accelerated and enhanced osteointegration of MAO-treated implants: histological and histomorphometric evaluation in a rabbit model
title_short Accelerated and enhanced osteointegration of MAO-treated implants: histological and histomorphometric evaluation in a rabbit model
title_sort accelerated and enhanced osteointegration of mao-treated implants: histological and histomorphometric evaluation in a rabbit model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944253/
https://www.ncbi.nlm.nih.gov/pubmed/29563493
http://dx.doi.org/10.1038/s41368-018-0008-z
work_keys_str_mv AT lixin acceleratedandenhancedosteointegrationofmaotreatedimplantshistologicalandhistomorphometricevaluationinarabbitmodel
AT xuhaiyang acceleratedandenhancedosteointegrationofmaotreatedimplantshistologicalandhistomorphometricevaluationinarabbitmodel
AT zhaobaodong acceleratedandenhancedosteointegrationofmaotreatedimplantshistologicalandhistomorphometricevaluationinarabbitmodel
AT jiangshuai acceleratedandenhancedosteointegrationofmaotreatedimplantshistologicalandhistomorphometricevaluationinarabbitmodel