Cargando…

Acylcarnitine Profiles in Plasma and Tissues of Hyperglycemic NZO Mice Correlate with Metabolite Changes of Human Diabetes

The New Zealand obese (NZO) mouse is a polygenic model for obesity and diabetes with obese females and obese, diabetes-prone males, used to study traits of the metabolic syndrome like type 2 diabetes mellitus (T2DM), obesity, and dyslipidaemia. By using LC-MS/MS, we here examine the suitability of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weiser, Anna, Giesbertz, Pieter, Daniel, Hannelore, Spanier, Britta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944288/ https://www.ncbi.nlm.nih.gov/pubmed/29854816 http://dx.doi.org/10.1155/2018/1864865

Ejemplares similares

Plasma acylcarnitine concentrations reflect the acylcarnitine profile in cardiac tissues
por: Makrecka-Kuka, Marina, et al.
Publicado: (2017)

Methionine restriction prevents onset of type 2 diabetes in NZO mice
por: Castaño-Martinez, Teresa, et al.
Publicado: (2019)

Metabolic changes during pregnancy in glucose‐intolerant NZO mice: A polygenic model with prediabetic metabolism
por: Grupe, Katharina, et al.
Publicado: (2020)

Plasma acylcarnitines are associated with pulmonary hypertension
por: Luo, Nancy, et al.
Publicado: (2017)

Influence of diet on visceral adipose remodeling in NONcNZO10 mice with polygenic susceptibility for type 2 diabetes
por: Adi, Nikhil, et al.
Publicado: (2012)

Plasma acylcarnitine levels increase with healthy aging
por: Jarrell, Zachery R., et al.
Publicado: (2020)

Altered Plasma Acylcarnitines and Amino Acids Profile in Spinocerebellar Ataxia Type 7
por: Nambo-Venegas, Rafael, et al.
Publicado: (2020)

E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice
por: Altenhofen, Delsi, et al.
Publicado: (2023)

Metabolite profiles of diabetes mellitus and response to intervention in anti-hyperglycemic drugs
por: Liu, Yanzhong, et al.
Publicado: (2023)

Changes in Amino Acid and Acylcarnitine Plasma Profiles for Distinguishing Patients with Multiple Sclerosis from Healthy Controls
por: Kasakin, Marat F., et al.
Publicado: (2020)

The brain acylcarnitine profile depends on nutritional state
por: Svalbe, Baiba, et al.
Publicado: (2015)

Acylcarnitine profiling by low-resolution LC-MS
por: Meierhofer, David
Publicado: (2019)

Plasma acylcarnitines and gut‐derived aromatic amino acids as sex‐specific hub metabolites of the human aging metabolome
por: Sol, Joaquim, et al.
Publicado: (2023)

Glyoxylate, a New Marker Metabolite of Type 2 Diabetes
por: Nikiforova, Victoria J., et al.
Publicado: (2014)

Increased Plasma Citrulline in Mice Marks Diet-Induced Obesity and May Predict the Development of the Metabolic Syndrome
por: Sailer, Manuela, et al.
Publicado: (2013)

The significance of acylcarnitine ratio indices in diagnosing carnitine-acylcarnitine translocase deficiency
por: Shi, Congcong, et al.
Publicado: (2023)

Acylcarnitine ratio indices in diagnosing carnitine-acylcarnitine translocase deficiency in newborns
por: Tan, Yifei, et al.
Publicado: (2023)

Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice
por: Bjørndal, Bodil, et al.
Publicado: (2018)

Plasma acylcarnitine in elderly Taiwanese: as biomarkers of possible sarcopenia and sarcopenia
por: Lo, Chi-Jen, et al.
Publicado: (2023)

Gut Microbiota and Acylcarnitine Metabolites Connect the Beneficial Association between Estrogen and Lipid Metabolism Disorders in Ovariectomized Mice
por: Guo, Mengmeng, et al.
Publicado: (2023)

GLP-1–oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice
por: Schwenk, Robert W., et al.
Publicado: (2014)

Dietary carbohydrates impair the protective effect of protein restriction against diabetes in NZO mice used as a model of type 2 diabetes
por: Laeger, Thomas, et al.
Publicado: (2018)

Dynamics and determinants of human plasma bile acid profiles during dietary challenges
por: Fiamoncini, Jarlei, et al.
Publicado: (2022)

Profiling the Oral Microbiome and Plasma Biochemistry of Obese Hyperglycemic Subjects in Qatar
por: Sohail, Muhammad U., et al.
Publicado: (2019)

Plasma acylcarnitine and diabetic retinopathy: A study from Eastern China
por: Jin, Dongzhen, et al.
Publicado: (2022)

Leptin, acylcarnitine metabolites and development of adiposity in the Rhea mother–child cohort in Crete, Greece
por: Perng, W., et al.
Publicado: (2016)

Dynamics of acylcarnitines, hypoglycin A, méthylènecyclopropylglycine and their metabolites in a Kladruber stallion with atypical myopathy
por: Jahn, Petr, et al.
Publicado: (2022)

Acylcarnitines profile best predicts survival in horses with atypical myopathy
por: Boemer, François, et al.
Publicado: (2017)

NMR Characterization of Long-Chain Fatty Acylcarnitine Binding to the Mitochondrial Carnitine/Acylcarnitine Carrier
por: Zhang, Ningning, et al.
Publicado: (2022)

Subchronic low-dose 2,4-D exposure changed plasma acylcarnitine levels and induced gut microbiome perturbations in mice
por: Tu, Pengcheng, et al.
Publicado: (2019)

Correlation between Acylcarnitine and Peripheral Neuropathy in Type 2 Diabetes Mellitus
por: An, Zhenni, et al.
Publicado: (2022)

Correlation of Serum Acylcarnitines with Clinical Presentation and Severity of Coronary Artery Disease
por: Deda, Olga, et al.
Publicado: (2022)

Plasma acylcarnitines could predict prognosis and evaluate treatment of IgA nephropathy
por: Xia, Fang-Ying, et al.
Publicado: (2019)

The accumulation of plasma acylcarnitines are associated with poor immune recovery in HIV-infected individuals
por: Qian, Shi, et al.
Publicado: (2021)

Association of plasma acylcarnitines and amino acids with hypertension: A nationwide metabolomics study
por: Arjmand, Babak, et al.
Publicado: (2023)

The Association Between Acylcarnitine Metabolites and Cardiovascular Disease in Chinese Patients With Type 2 Diabetes Mellitus
por: Zhao, Shuo, et al.
Publicado: (2020)

Similarities between acylcarnitine profiles in large for gestational age newborns and obesity
por: Sánchez-Pintos, Paula, et al.
Publicado: (2017)

Anti-Insulin Receptor Autoantibodies Are Not Required for Type 2 Diabetes Pathogenesis in NZL/Lt Mice, a New Zealand Obese (NZO)-Derived Mouse Strain
por: McInerney, Marcia F., et al.
Publicado: (2004)

A low-carbohydrate high-fat diet increases weight gain and does not improve glucose tolerance, insulin secretion or β-cell mass in NZO mice
por: Lamont, B J, et al.
Publicado: (2016)

Enhanced Acylcarnitine Annotation in High-Resolution Mass Spectrometry Data: Fragmentation Analysis for the Classification and Annotation of Acylcarnitines
por: van der Hooft, Justin J. J., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_80f0q5irhajck1t57ulvodltef