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Crystallization and structure analysis of the core motif of the Pks13 acyltransferase domain from Mycobacterium tuberculosis

Type I polyketide synthase 13 (Pks13) is involved in the final step of the biosynthesis of mycolic acid in Mycobacterium tuberculosis. Recent articles have reported that Pks13 is an essential enzyme in the mycolic acid biosynthesis pathway, and it has been deeply studied as a drug target in Tubercul...

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Detalles Bibliográficos
Autores principales:	Yu, Mingjing, Dou, Chao, Gu, Yijun, Cheng, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2018
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944431/ https://www.ncbi.nlm.nih.gov/pubmed/29761048 http://dx.doi.org/10.7717/peerj.4728

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