Cargando…

Phase I study of cord blood transplantation with intrabone marrow injection of mesenchymal stem cells: A clinical study protocol

INTRODUCTION: Delayed hematological recovery, graft failure, and acute graft-versus-host disease (GVHD) still remain major problems in cord blood transplantation (CBT). Mesenchymal stem cells (MSCs) are known to support bone marrow stroma and promote hematopoiesis. Additionally, MSCs possess immunom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goto, Tatsunori, Murata, Makoto, Terakura, Seitaro, Nishida, Tetsuya, Adachi, Yoshiya, Ushijima, Yoko, Shimada, Kazuyuki, Ishikawa, Yuichi, Hayakawa, Fumihiko, Nishio, Nobuhiro, Nishiwaki, Satoshi, Hirakawa, Akihiro, Kato, Katsuyoshi, Takahashi, Yoshiyuki, Kiyoi, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944542/ https://www.ncbi.nlm.nih.gov/pubmed/29702996 http://dx.doi.org/10.1097/MD.0000000000010449

Ejemplares similares

Phase I clinical trial of intra‐bone marrow cotransplantation of mesenchymal stem cells in cord blood transplantation
por: Goto, Tatsunori, et al.
Publicado: (2020)

Phase II study of intrabone single unit cord blood transplantation for hematological malignancies
por: Murata, Makoto, et al.
Publicado: (2017)

Identification of the novel deletion-type PML-RARA mutation associated with the retinoic acid resistance in acute promyelocytic leukemia
por: Hattori, Hikaru, et al.
Publicado: (2018)

High incidence of extensive chronic graft-versus-host disease in patients with the REG3A rs7588571 non-GG genotype
por: Koyama, Daisuke, et al.
Publicado: (2017)

Efficacy and safety of autologous peripheral blood stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia: A study protocol for a multicenter exploratory prospective study (Auto-Ph17 study)
por: Nishiwaki, Satoshi, et al.
Publicado: (2017)

Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells
por: Sugimoto, Keiki, et al.
Publicado: (2015)

SPIB is a novel prognostic factor in diffuse large B‐cell lymphoma that mediates apoptosis via the PI3K‐AKT pathway
por: Takagi, Yusuke, et al.
Publicado: (2016)

Identification of volasertib-resistant mechanism and evaluation of combination effects with volasertib and other agents on acute myeloid leukemia
por: Adachi, Yoshiya, et al.
Publicado: (2017)

Artificial T Cell Adaptor Molecule-Transduced TCR-T Cells Demonstrated Improved Proliferation Only When Transduced in a Higher Intensity
por: Sakai, Toshiyasu, et al.
Publicado: (2020)

Pyruvate secreted from patient‐derived cancer‐associated fibroblasts supports survival of primary lymphoma cells
por: Sakamoto, Akihiko, et al.
Publicado: (2018)

Intrabone Transplant of Cord Blood Stem Cells Establishes a Local Engraftment Store: A Functional PET/FDG Study
por: Marini, Cecilia, et al.
Publicado: (2012)

Peripheral blood cell‐free DNA is an alternative tumor DNA source reflecting disease status in myelodysplastic syndromes
por: Suzuki, Yasuhiro, et al.
Publicado: (2016)

Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism
por: Aoki, Tomohiro, et al.
Publicado: (2016)

Current progress and future perspectives of research on intravascular large B‐cell lymphoma
por: Shimada, Kazuyuki, et al.
Publicado: (2021)

Intrabone transplant provides full stemness of cord blood stem cells with fast hematopoietic recovery and low GVHD rate: results from a prospective study
por: Bonifazi, Francesca, et al.
Publicado: (2018)

Exosomes secreted from cancer-associated fibroblasts elicit anti-pyrimidine drug resistance through modulation of its transporter in malignant lymphoma
por: Kunou, Shunsuke, et al.
Publicado: (2021)

Multi-Lineage BCR-ABL Expression in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Is Associated With Improved Prognosis but No Specific Molecular Features
por: Nishiwaki, Satoshi, et al.
Publicado: (2020)

Dexamethasone Palmitate Ameliorates Macrophages-Rich Graft-versus-Host Disease by Inhibiting Macrophage Functions
por: Nishiwaki, Satoshi, et al.
Publicado: (2014)

3rd International Symposium on Dynamical Processes at Solid Surfaces
por: Murata, Yoshitada, et al.
Publicado: (1993)

Machine learning-aided risk stratification in Philadelphia chromosome-positive acute lymphoblastic leukemia
por: Nishiwaki, Satoshi, et al.
Publicado: (2021)

De novo diffuse large B-cell lymphoma with a CD20 immunohistochemistry-positive and flow cytometry-negative phenotype: Molecular mechanisms and correlation with rituximab sensitivity
por: Tokunaga, Takashi, et al.
Publicado: (2014)

Enrichment of T-cell proliferation and memory gene signatures of CD79A/CD40 costimulatory domain potentiates CD19CAR-T cell functions
por: Ung, Socheatraksmey, et al.
Publicado: (2022)

Clinical and pathological features of five-year survivors after pancreatectomy for pancreatic adenocarcinoma
por: Kimura, Kenjiro, et al.
Publicado: (2014)

Small‐molecule Hedgehog inhibitor attenuates the leukemia‐initiation potential of acute myeloid leukemia cells
por: Fukushima, Nobuaki, et al.
Publicado: (2016)

BCL6 inhibition ameliorates resistance to ruxolitinib in CRLF2-rearranged acute lymphoblastic leukemia
por: Tsuzuki, Shinobu, et al.
Publicado: (2022)

Symptom Improvement of ulceRative colitis after an Induction dose of UStekinumab in Japanese clinical practice (SIRIUS), measured using patient-reported outcomes: a prospective observational study
por: Matsuoka, Katsuyoshi, et al.
Publicado: (2022)

Treatment procedures and associated medical costs of methicillin-resistant Staphylococcus aureus infection in Japan: A retrospective analysis using a database of Japanese employment-based health insurance
por: Yuasa, Akira, et al.
Publicado: (2019)

FLT3 mutations in acute myeloid leukemia: Therapeutic paradigm beyond inhibitor development
por: Kiyoi, Hitoshi, et al.
Publicado: (2019)

The photosensitizer verteporfin has light-independent anti-leukemic activity for Ph-positive acute lymphoblastic leukemia and synergistically works with dasatinib
por: Morishita, Takanobu, et al.
Publicado: (2016)

Fibcare(®) shows correlation with fibrinogen levels by the Clauss method during cardiopulmonary bypass
por: Yamada, Akihiro, et al.
Publicado: (2023)

Exploring the threshold for the start of respiratory syncytial virus infection epidemic season using sentinel surveillance data in Japan
por: Miyama, Takeshi, et al.
Publicado: (2023)

Combination of tumor necrosis factor‐α and epidermal growth factor induces the adrenergic‐to‐mesenchymal transdifferentiation in SH‐SY5Y neuroblastoma cells
por: Huang, Yue, et al.
Publicado: (2020)

Diagnostic accuracy of percutaneous core biopsy before cryoablation for small-sized renal cell carcinoma
por: Ushijima, Yasuhiro, et al.
Publicado: (2023)

Comparison of clonal architecture between primary and immunodeficient mouse-engrafted acute myeloid leukemia cells
por: Kawashima, Naomi, et al.
Publicado: (2022)

Randomised controlled trial of conditioning regimen for cord blood transplantation for adult myeloid malignancies comparing high-dose cytarabine/cyclophosphamide/total body irradiation with versus without G-CSF priming: G-CONCORD study protocol
por: Terakura, Seitaro, et al.
Publicado: (2020)

Superconducting-Gap Anisotropy of Iron Pnictides Investigated via Combinatorial Microwave Measurements
por: Okada, Tatsunori, et al.
Publicado: (2020)

Establishment and characterization of new cell lines of anaplastic pancreatic cancer, which is a rare malignancy: OCUP-A1 and OCUP-A2
por: Miura, Kotaro, et al.
Publicado: (2016)

Predictive factors of acute respiratory events during initial induction chemotherapy in patients with advanced neuroblastoma
por: Matsui, Motohiro, et al.
Publicado: (2021)

Alkyl hydroperoxide reductase enhances the growth of Leuconostoc mesenteroides lactic acid bacteria at low temperatures
por: Goto, Seitaro, et al.
Publicado: (2015)

Pembrolizumab monotherapy in Japanese patients with advanced ovarian cancer: Subgroup analysis from the KEYNOTE‐100
por: Nishio, Shin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_022khq36tug9aavbp21eao9c8b