NI‐0801, an anti‐chemokine (C‐X‐C motif) ligand 10 antibody, in patients with primary biliary cholangitis and an incomplete response to ursodeoxycholic acid

NI‐0801 is a fully human monoclonal antibody against chemokine (C‐X‐C motif) ligand 10 (CXCL10), which is involved in the recruitment of inflammatory T cells into the liver. The safety and efficacy of NI‐0801 was assessed in patients with primary biliary cholangitis. In this open‐label phase 2a stud...

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Detalles Bibliográficos
Autores principales: de Graaf, Kathy L., Lapeyre, Geneviève, Guilhot, Florence, Ferlin, Walter, Curbishley, Stuart M., Carbone, Marco, Richardson, Paul, Moreea, Sulleman, McCune, C. Anne, Ryder, Stephen D., Chapman, Roger W., Floreani, Annarosa, Jones, David E., de Min, Cristina, Adams, David H., Invernizzi, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944576/
https://www.ncbi.nlm.nih.gov/pubmed/29761166
http://dx.doi.org/10.1002/hep4.1170

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