Cytochrome P450 Genetic Variation Associated with Tamoxifen Biotransformation in American Indian and Alaska Native People

Despite evidence that pharmacogenetics can improve tamoxifen pharmacotherapy, there are few studies with American Indian and Alaska Native (AIAN) people. We examined variation in cytochrome P450 (CYP) genes (CYP2D6, CYP3A4, CYP3A5, and CYP2C9) and tamoxifen biotransformation in AIAN patients with br...

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Detalles Bibliográficos
Autores principales: Khan, Burhan A., Robinson, Renee, Fohner, Alison E., Muzquiz, LeeAnna I., Schilling, Brian D., Beans, Julie A., Olnes, Matthew J., Trawicki, Laura, Frydenlund, Holly, Laukes, Cindi, Beatty, Patrick, Phillips, Brian, Nickerson, Deborah, Howlett, Kevin, Dillard, Denise A., Thornton, Timothy A., Thummel, Kenneth E., Woodahl, Erica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944577/
https://www.ncbi.nlm.nih.gov/pubmed/29436156
http://dx.doi.org/10.1111/cts.12542

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