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Tacrolimus intra-patient variability is not associated with chronic active antibody mediated rejection

BACKGROUND: Chronic active antibody mediated rejection (c-aABMR) is a major cause of long-term kidney allograft loss. It is hypothesized that frequent sub-therapeutic exposure to immunosuppressive drugs, in particular tacrolimus (Tac), is a risk factor for the development of c-aABMR. The intra-patie...

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Detalles Bibliográficos
Autores principales: Sablik, Kasia A., Clahsen-van Groningen, Marian C., Hesselink, Dennis A., van Gelder, Teun, Betjes, Michiel G. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944964/
https://www.ncbi.nlm.nih.gov/pubmed/29746495
http://dx.doi.org/10.1371/journal.pone.0196552