Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research

Monocyte-like cell lines (MCLCs), including THP-1, HL-60 and U-937 cells, are used routinely as surrogates for isolated human peripheral blood mononuclear cells (PBMCs). To systematically evaluate these immortalised cells and PBMCs as model systems to study inflammation relevant to the pathogenesis...

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Detalles Bibliográficos
Autores principales: Riddy, Darren M., Goy, Emily, Delerive, Philippe, Summers, Roger J., Sexton, Patrick M., Langmead, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944989/
https://www.ncbi.nlm.nih.gov/pubmed/29746559
http://dx.doi.org/10.1371/journal.pone.0197177

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