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A flavin-dependent halogenase from metagenomic analysis prefers bromination over chlorination

Flavin-dependent halogenases catalyse halogenation of aromatic compounds. In most cases, this reaction proceeds with high regioselectivity and requires only the presence of FADH(2), oxygen, and halide salts. Since marine habitats contain high concentrations of halides, organisms populating the ocean...

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Detalles Bibliográficos
Autores principales: Neubauer, Pia R., Widmann, Christiane, Wibberg, Daniel, Schröder, Lea, Frese, Marcel, Kottke, Tilman, Kalinowski, Jörn, Niemann, Hartmut H., Sewald, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945002/
https://www.ncbi.nlm.nih.gov/pubmed/29746521
http://dx.doi.org/10.1371/journal.pone.0196797