Depletion of mRNA export regulator DBP5/DDX19, GLE1 or IPPK that is a key enzyme for the production of IP(6), resulting in differentially altered cytoplasmic mRNA expression and specific cell defect

DBP5, also known as DDX19, GLE1 and inositol hexakisphosphate (IP(6)) function in messenger RNA (mRNA) export at the cytoplasmic surface of the nuclear pore complex in eukaryotic cells. DBP5 is a DEAD-box RNA helicase, and its activity is stimulated by interactions with GLE1 and IP(6). In addition,...

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Detalles Bibliográficos
Autores principales: Okamura, Masumi, Yamanaka, Yasutaka, Shigemoto, Maki, Kitadani, Yuya, Kobayashi, Yuhko, Kambe, Taiho, Nagao, Masaya, Kobayashi, Issei, Okumura, Katsuzumi, Masuda, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945018/
https://www.ncbi.nlm.nih.gov/pubmed/29746542
http://dx.doi.org/10.1371/journal.pone.0197165

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