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Effects of collagen matrix and bioreactor cultivation on cartilage regeneration of a full-thickness critical-size knee joint cartilage defects with subchondral bone damage in a rabbit model
Cartilage has limited self-repair ability. The purpose of this study was to investigate the effects of different species of collagen-engineered neocartilage for the treatment of critical-size defects in the articular joint in a rabbit model. Type II and I collagen obtained from rabbits and rats was...
Autores principales: | Wang, Kuo-Hwa, Wan, Richard, Chiu, Li-Hsuan, Tsai, Yu-Hui, Fang, Chia-Lang, Bowley, John F., Chen, Kuan-Chou, Shih, Hsin-Nung, Lai, Wen-Fu Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945026/ https://www.ncbi.nlm.nih.gov/pubmed/29746554 http://dx.doi.org/10.1371/journal.pone.0196779 |
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