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The protective effect of the EP2 receptor on TGF-β1 induced podocyte injury via the PI3K / Akt signaling pathway

Transforming growth factor β1 (TGF-β1) plays a central role in chronic kidney diseases. TGF-β1 induction causes podocyte injury, which results in proteinuria and renal failure. However, the effect of the prostaglandin E2 /E-prostanoid receptor (EP2) on TGF-β1-induced podocyte injury remains unknown....

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Detalles Bibliográficos
Autores principales:	Liu, Jing, Zhang, Yi-de, Chen, Xiao-lan, Zhu, Xue-ling, Chen, Xu, Wu, Jian-hua, Guo, Nai-feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945042/ https://www.ncbi.nlm.nih.gov/pubmed/29746568 http://dx.doi.org/10.1371/journal.pone.0197158

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